Drugs / doxecitine

Regulatory milestones approvals, filings & regulatory actions · 2 recorded

MilestoneJurisdictionBrandIndicationDateSentence it was read from
Approved EU (EMA) Kygevvi — 2026-03-26 europa.eu ↗
Approved US (FDA) KYGEVVI — 2025-11-03 fda.gov ↗

Trials 8

199519961997199819992000200120022003200420052006200720082009201020112012201320142015201620172018201920202021202220232024202520262027202820292030
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 12 trials
Phase 1 NCT06817590 Sep 2025 → Jun 2028 expected Hoyeraal-Hreidarsson syndrome, Revesz syndrome, pulmonary fibrosis and/or bone marrow failure, telomere-related Suneet Agarwal Recruiting No outcome recorded
Phase 1 NCT00002818 Feb 1995 → Feb 2001 leukemia, plasma cell neoplasm, poisoning Virginia Commonwealth University Completed No outcome recorded
Phase 1/21 trial
Phase 1/2 NCT03639701 May 2017 → Dec 2026 expected mitochondrial DNA depletion syndrome, myopathic form Columbia University Active not recruiting No outcome recorded
Phase 23 trials
Phase 2 NCT06754098 Jan 2025 → Jan 2027 expected inborn mitochondrial myopathy, mitochondrial DNA depletion syndrome, myopathic form Cristina Domínguez González Recruiting No outcome recorded
Phase 2 NCT04802707 Oct 2021 → Jun 2029 expected mitochondrial DNA depletion syndrome, mitochondrial encephalomyopathy Kenneth Myers, MD Recruiting No outcome recorded
Phase 2 NCT03845712 Jul 2019 → Jul 2026 overdue mitochondrial DNA depletion syndrome, myopathic form UCB BIOSCIENCES, Inc. Active not recruiting No outcome recorded
Phase 31 trial
Phase 3 NCT04581733 Sep 2022 → Mar 2025 mitochondrial DNA depletion syndrome, myopathic form Zogenix MDS, Inc. Withdrawn No outcome recorded Stop: Business
Phase not stated1 trial
— NCT06590493 — mitochondrial DNA depletion syndrome, myopathic form UCB BIOSCIENCES, Inc. Available No outcome recorded

Evidence & citations 8 cited values

Every value below carries the sentence it was read from. 9 sources stand behind the page.

FieldValueCited text
Known as doxecitine ClinicalTrials.gov intervention name — accepted as the source's own label NCT06590493 ↗
2

NCT03845712 ↗

NCT06754098 ↗

Known as 2'-deoxycytidine ChEMBL registry synonym — accepted as the source's own label CHEMBL66115 ↗
Known as dCyt “open label deoxythymidine (dThd) and deoxycytidine (dCyt), which are nucleotide precursors” NCT03639701 ↗
Known as Deoxycytidine “Treatment of TK2 Deficiency With Thymidine and Deoxycytidine” NCT03639701 ↗
4

“Deoxycytidine (dC) and deoxythymidine (dT)” NCT04581733 ↗

NCT00002818 ↗

NCT04802707 ↗

NCT06817590 ↗

Known as Doxecitine component of mt-1621 2'-deoxycytidine ChEMBL registry synonym — accepted as the source's own label CHEMBL66115 ↗
Known as MT1621 (dC) ChEMBL registry synonym — accepted as the source's own label CHEMBL66115 ↗
Modality Small molecule “Combination Pyrimidine Nucleosides” NCT03845712 ↗
1

CHEMBL66115 ↗

Route Intravenous “Patients receive deoxycytidine IV over 120 hours” NCT00002818 ↗