Drugs / Sepranolone
Sepranolone
also known as
Allopregnan-3.beta.-ol-20-one · Epiallopregnanolone · Isoallopregnanolone · Isopregnanolone · NSC-97078 · Sepranolona · U-0949 · UC1010
Trials 3
| Phase | Registry id | Dates | Indication | Sponsor | Status | Outcome |
|---|---|---|---|---|---|---|
| Phase 23 trials | ||||||
| Phase 2 | NCT05434546 | Feb 2022 → Feb 2023 | Tourette syndrome | Asarina Pharma | Completed | No outcome recorded |
| Phase 2 | NCT04102995 | Aug 2019 → May 2021 | migraine disorder | Asarina Pharma | Completed | No outcome recorded |
| Phase 2 | NCT03697265 | Apr 2018 → Jul 2020 | premenstrual dysphoric disorder | Asarina Pharma | Completed | No outcome recorded |
| Comparator or background therapy1 trial | ||||||
| Phase 1/2 | NCT01875718 Comparator | Jan 2013 → Jun 2014 | premenstrual dysphoric disorder | Umecrine Mood AB | Completed | No outcome recorded |
Press releases naming this drug 1 release
| Date | Issuer | Release |
|---|---|---|
| 2026-06-11 | Relmada Therapeutics, Inc. | Relmada Therapeutics Appoints CNS Drug Development Veteran Michael Quirk as Senior Advisor for Sepranolone Program relmada.com ↗ |
Evidence & citations 11 cited values
Every value below carries the sentence it was read from. 5 sources stand behind the page.
| Field | Value | Cited text |
|---|---|---|
| Known as | Sepranolone | ClinicalTrials.gov intervention name — accepted as the source's own label NCT05434546 ↗ |
| Known as | Allopregnan-3.beta.-ol-20-one | ChEMBL registry synonym — accepted as the source's own label CHEMBL2057301 ↗ |
| Known as | Epiallopregnanolone | ChEMBL registry synonym — accepted as the source's own label CHEMBL2057301 ↗ |
| Known as | Isoallopregnanolone | ChEMBL registry synonym — accepted as the source's own label CHEMBL2057301 ↗ |
| Known as | Isopregnanolone | ChEMBL registry synonym — accepted as the source's own label CHEMBL2057301 ↗ |
| Known as | NSC-97078 | ChEMBL registry synonym — accepted as the source's own label CHEMBL2057301 ↗ |
| Known as | Sepranolona | ChEMBL registry synonym — accepted as the source's own label CHEMBL2057301 ↗ |
| Known as | U-0949 | ChEMBL registry synonym — accepted as the source's own label CHEMBL2057301 ↗ |
| Known as | UC1010 | ClinicalTrials.gov intervention name — accepted as the source's own label NCT01875718 ↗ |
| Modality | Small molecule | “Sepranolone is an endogenous steroid.” NCT03697265 ↗ |
| Route | Subcutaneous | “UC1010 when administered subcutaneously as a single dose” NCT01875718 ↗ |