Drugs / Trimegestone
last change Feb 2018 re-read 2 minutes ago

Trimegestone

also known as TMG · RU 27987 · Trimegestona

Small molecule targets PGR via activation

Developed for
pregnancy disorder
Investigated by
Galeno Desenvolvimento de Pesquisas Clínicas · SocraTec R&D GmbH · Wyeth is now a wholly owned subsidiary of Pfizer

Trials 2 · a red edge is where a trial was stopped

20052006200720082009201020112012201320142015201620172018201920202021202220232024202520262027
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 11 trial
Phase 1 NCT03343912 Nov 2017 → Jan 2018 pregnancy disorder Galeno Desenvolvimento de Pesquisas Clínicas Completed No outcome recorded
Phase 41 trial
Phase 4 NCT00195455 Feb 2005 → Mar 2007 Wyeth is now a wholly owned subsidiary of Pfizer Completed No outcome recorded
Also used as a comparator or background therapy in 1 trial
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 4 NCT00472004 Comparator Feb 2006 → Dec 2009 Wyeth is now a wholly owned subsidiary of Pfizer Completed No outcome recorded

Evidence & citations 8 cited values

Every value below carries the sentence it was read from. 4 sources stand behind the page.

FieldValueCited text
Known as Trimegestone “17B Estradiol (1mg) / (0.125 mg) Trimegestone (TMG) Continuous combined, 1 Daily, 1 year duration” NCT00472004
2

NCT00195455

NCT03343912

Known as RU 27987 ChEMBL registry synonym — accepted as the source's own label CHEMBL2104765
Known as TMG “Vaginal ring with a nominal delivery rate of 0.400 mg/d estriol (E3) and 0.06 mg/d trimegestone (TMG), vaginal application” NCT03343912
1

“17B Estradiol (1mg) / (0.125 mg) Trimegestone (TMG) Continuous combined, 1 Daily, 1 year duration” NCT00472004

Known as Trimegestona ChEMBL registry synonym — accepted as the source's own label CHEMBL2104765
Action Activate “Progesterone receptor agonist” CHEMBL2104765
Modality Small molecule CHEMBL2104765
Route Other “vaginal application” NCT03343912
Target PGR “Progesterone receptor agonist” CHEMBL2104765