Drugs / MK-3415
last change Jan 2017 re-read 2 minutes ago

MK-3415

also known as actoxumab · MDX-066

Monoclonal antibody

Developed for
Clostridium difficile colitis
Investigated by
Merck Sharp & Dohme LLC

Trials 2 · a red edge is where a trial was stopped

2012201320142015201620172018201920202021202220232024202520262027
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 3 NCT01513239 Feb 2012 → May 2015 Clostridium difficile colitis Merck Sharp & Dohme LLC Completed No outcome recorded
Phase 3 NCT01241552 Oct 2011 → Dec 2014 Clostridium difficile colitis Merck Sharp & Dohme LLC Completed No outcome recorded

Evidence & citations 5 cited values

Every value below carries the sentence it was read from. 3 sources stand behind the page.

FieldValueCited text
Known as MK-3415 ClinicalTrials.gov intervention name — accepted as the source's own label NCT01241552
Known as actoxumab Actoxumab and bezlotoxumab are human monoclonal antibodies against C. difficile toxins A and B, respectively.” PMID 28121498 Jan 2017
Known as MDX-066 ChEMBL registry synonym — accepted as the source's own label CHEMBL2109312
Modality Monoclonal antibody “Actoxumab and bezlotoxumab are human monoclonal antibodies against C. difficile toxins A and B, respectively.” PMID 28121498 Jan 2017
Route Intravenous “Single intravenous (IV) infusion of 10 mg/kg MK-3415” NCT01241552