Drugs / BMS-582949
last change Mar 2015 re-read 2 minutes ago

BMS-582949

also known as PS-540446

Small molecule targets MAPK14 via inhibition

Developed for
rheumatoid arthritis · vascular disorder · psoriasis
Investigated by
Bristol-Myers Squibb

Trials 3 · a red edge is where a trial was stopped

2006200720082009201020112012201320142015201620172018201920202021202220232024202520262027
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 11 trial
Phase 1 NCT00162292 Nov 2005 → Oct 2007 rheumatoid arthritis Bristol-Myers Squibb Completed No outcome recorded
Phase 22 trials
Phase 2 NCT00570752 Dec 2008 → Nov 2010 vascular disorder Bristol-Myers Squibb Completed No outcome recorded
Phase 2 NCT00605735 Mar 2008 → Aug 2009 rheumatoid arthritis Bristol-Myers Squibb Completed No outcome recorded
Also used as a comparator or background therapy in 1 trial
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 2 NCT00399906 Comparator Aug 2007 → Jan 2009 psoriasis Bristol-Myers Squibb Completed No outcome recorded

Evidence & citations 6 cited values

Every value below carries the sentence it was read from. 6 sources stand behind the page.

FieldValueCited text
Known as BMS-582949 ClinicalTrials.gov intervention name — accepted as the source's own label NCT00162292
3

NCT00570752

NCT00605735

NCT00399906

Known as PS-540446 ChEMBL registry synonym — accepted as the source's own label CHEMBL1230065
Action Inhibit “MAP kinase p38 alpha inhibitor” CHEMBL1230065
1

“p38MAPK inhibitor” PMID 25913664 Mar 2015

Modality Small molecule CHEMBL1230065
Route Oral “Tablets, Oral, Once daily, 12 weeks” NCT00399906
Target MAPK14 “MAP kinase p38 alpha inhibitor” CHEMBL1230065