Drugs / MK-8457
last change Oct 2013 re-read 3 minutes ago

MK-8457

Small molecule

Developed for
rheumatoid arthritis · hypertensive disorder
Investigated by
Merck Sharp & Dohme LLC

Trials 3

2012201320142015201620172018201920202021202220232024202520262027
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 11 trial · 1 missed
Phase 1 NCT01446003 Oct 2011 → Feb 2012 hypertensive disorder Merck Sharp & Dohme LLC Completed Missed primary
Phase 22 trials · 1 met primary · 1 missed
Phase 2 NCT01651936 Aug 2012 → Oct 2013 rheumatoid arthritis Merck Sharp & Dohme LLC Terminated Missed primary
Phase 2 NCT01569152 May 2012 → Oct 2013 rheumatoid arthritis Merck Sharp & Dohme LLC Terminated Met primary

Evidence & citations 3 cited values

Every value below carries the sentence it was read from. 4 sources stand behind the page.

FieldValueCited text
Known as MK-8457 ClinicalTrials.gov intervention name — accepted as the source's own label NCT01651936 ↗
2

NCT01569152 ↗

NCT01446003 ↗

Modality Small molecule — CHEMBL3685811 ↗
Route Oral “dosed orally BID” NCT01569152 ↗