Drugs / BMS-823778
last change May 2016 re-read 3 minutes ago

BMS-823778

Small molecule targets HSD11B1 via inhibition

Developed for
atherosclerotic cardiovascular disease · hyperlipidemia · hypertensive disorder · type 2 diabetes mellitus
Investigated by
Bristol-Myers Squibb

Trials 4

201020112012201320142015201620172018201920202021202220232024202520262027
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 11 trial
Phase 1 NCT01515202 Mar → Sep 2012 type 2 diabetes mellitus Bristol-Myers Squibb Completed No outcome recorded
Phase 23 trials
Phase 2 NCT01666704 Apr 2014 → Oct 2015 atherosclerotic cardiovascular disease Bristol-Myers Squibb Withdrawn No outcome recorded
Phase 2 NCT01602367 Jul → Nov 2012 hypertensive disorder Bristol-Myers Squibb Terminated No outcome recorded
Phase 2 NCT01112423 Jun → Dec 2010 hyperlipidemia Bristol-Myers Squibb Completed No outcome recorded
Comparator or background therapy1 trial
Phase 2 NCT01111955 Comparator Jul 2010 → Jan 2011 type 2 diabetes mellitus Bristol-Myers Squibb Completed No outcome recorded

Evidence & citations 5 cited values

Every value below carries the sentence it was read from. 6 sources stand behind the page.

FieldValueCited text
Known as BMS-823778 “Drug: BMS-823778” NCT01515202 ↗
4

NCT01666704 ↗

NCT01602367 ↗

NCT01111955 ↗

NCT01112423 ↗

Action Inhibit “11-beta-hydroxysteroid dehydrogenase 1 inhibitor” CHEMBL4301600 ↗
Modality Small molecule — CHEMBL4301600 ↗
Route Oral “Capsules, Oral, 2 mg, once daily, 28 days” NCT01111955 ↗
Target HSD11B1 “11-beta-hydroxysteroid dehydrogenase 1 inhibitor” CHEMBL4301600 ↗