Drugs / Efavaleukin alfa
last change Oct 2024 re-read 3 minutes ago

Efavaleukin alfa

Protein / enzyme biologic

Developed for
chronic graft versus host disease · systemic lupus erythematosus · ulcerative colitis · rheumatoid arthritis
Investigated by
Amgen

Trials 9

PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 14 trials
Phase 1 NCT04987333 Aug 2021 → Oct 2022 inflammatory disease Amgen Completed No outcome recorded
Phase 1 NCT05885451 Jan → Apr 2019 chronic graft versus host disease Amgen Completed No outcome recorded
Phase 1 NCT03451422 Apr 2018 → Oct 2021 systemic lupus erythematosus Amgen Completed No outcome recorded
Phase 1 NCT05873907 Oct 2015 → Jun 2017 chronic graft versus host disease Amgen Completed No outcome recorded
Phase 1/22 trials
Phase 1/2 NCT03410056 May 2018 → Dec 2019 rheumatoid arthritis Amgen Terminated No outcome recorded Stop: Business
Phase 1/2 NCT03422627 Apr 2018 → Oct 2022 chronic graft versus host disease Amgen Terminated No outcome recorded Stop: Business
Phase 23 trials · 2 missed
Phase 2 NCT05672199 Apr 2023 → Oct 2024 ulcerative colitis Amgen Terminated No outcome recorded
Phase 2 NCT04987307 Jan 2022 → Oct 2024 ulcerative colitis Amgen Terminated Missed primary
Phase 2 NCT04680637 May 2021 → May 2023 systemic lupus erythematosus Amgen Terminated Missed primary

Evidence & citations 6 cited values

Every value below carries the sentence it was read from. 10 sources stand behind the page.

FieldValueCited text
Known as Efavaleukin alfa ClinicalTrials.gov intervention name — accepted as the source's own label NCT04987333 ↗
6

NCT03422627 ↗

NCT04987307 ↗

NCT05672199 ↗

NCT03451422 ↗

NCT04680637 ↗

NCT03410056 ↗

Known as AMG 592 ClinicalTrials.gov intervention name — accepted as the source's own label NCT05885451 ↗
1

NCT05873907 ↗

Known as Efavaleukina alfa ChEMBL registry synonym — accepted as the source's own label CHEMBL4298204 ↗
Known as Efavaleukine alfa ChEMBL registry synonym — accepted as the source's own label CHEMBL4298204 ↗
Modality Protein / enzyme biologic — CHEMBL4298204 ↗
Route Subcutaneous “Efavaleukin alfa administered as a subcutaneous injection.” NCT03410056 ↗