Drugs / LB-102
last change Jul 2026 re-read 3 minutes ago

LB-102

also known as N-Methyl amisulpride

Small molecule

Developed for
schizophrenia · bipolar I disorder
Investigated by
LB Pharmaceuticals Inc. · Washington University School of Medicine

Trials 4

PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 11 trial
Phase 1 NCT04588129 Jan → Sep 2021 schizophrenia LB Pharmaceuticals Inc. Completed No outcome recorded
Phase 21 trial · 1 met primary
Phase 2 NCT06179108 Nov 2023 → Dec 2024 schizophrenia LB Pharmaceuticals Inc. Completed Met primary
Phase 32 trials
Phase 3 NCT07369154 Apr 2026 → Dec 2028 expected schizophrenia LB Pharmaceuticals Inc. Not yet recruiting No outcome recorded
Phase 3 NCT07363577 Mar 2026 → Jun 2027 expected schizophrenia LB Pharmaceuticals Inc. Recruiting No outcome recorded
Comparator or background therapy2 trials
Phase 1 NCT04187560 Comparator Jan → Jul 2020 schizophrenia LB Pharmaceuticals Inc. Completed No outcome recorded
Phase 2 NCT07494305 Comparator Jan 2026 → Feb 2028 expected bipolar I disorder LB Pharmaceuticals Inc. Recruiting No outcome recorded

Evidence & citations 5 cited values

Every value below carries the sentence it was read from. 7 sources stand behind the page.

FieldValueCited text
Known as LB-102 ClinicalTrials.gov intervention name — accepted as the source's own label NCT07494305 ↗
5

NCT04588129 ↗

NCT04187560 ↗

NCT07363577 ↗

NCT07369154 ↗

NCT06179108 ↗

Known as N-Methyl amisulpride “LB-102 (N-Methyl amisulpride) formulated capsule will be administered orally once daily for one day in 4 subjects.” NCT04588129 ↗
2

“LB-102 (N-methyl amisulpride) is a novel benzamide under investigation for the treatment of schizophrenia.” PMID 42018313 ↗ Jul 2026

“LB-102 N-Methyl amisulpride)” NCT04187560 ↗

Action Inhibit “LB-102 is a dopamine D2/3 and 5HT7 antagonist.” NCT06179108 ↗
Modality Small molecule “LB-102 (N-methyl amisulpride) is a novel benzamide under investigation for the treatment of schizophrenia.” PMID 42018313 ↗ Jul 2026
Route Oral “LB-102 Administered Orally” NCT04187560 ↗