Drugs / human recombinant Bone Morphogenetic Protein 4
last change Aug 2023 re-read 3 minutes ago

human recombinant Bone Morphogenetic Protein 4

also known as hrBMP4 · R-hbmp4

Protein / enzyme biologic

Developed for
glioblastoma
Investigated by
ORION Clinical Services · Stemgen

Trials 1

2018201920202021202220232024202520262027
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 1 NCT02869243 Jul 2017 → Oct 2020 glioblastoma Stemgen Completed No outcome recorded

Evidence & citations 6 cited values

Every value below carries the sentence it was read from. 3 sources stand behind the page.

FieldValueCited text
Known as human recombinant Bone Morphogenetic Protein 4 “BACKGROUND: This Phase 1 study evaluates the intra- and peritumoral administration by convection enhanced delivery (CED) of human recombinant Bone Morphogenetic Protein 4...” PMID 37563568 ↗ Aug 2023
Known as hrBMP4 ClinicalTrials.gov intervention name — accepted as the source's own label NCT02869243 ↗
Known as R-hbmp4 ChEMBL registry synonym — accepted as the source's own label CHEMBL4594551 ↗
Action Inhibit “hrBMP4) - an inhibitory regulator of cancer stem cells (CSCs)” PMID 37563568 ↗ Aug 2023
Modality Protein / enzyme biologic “human recombinant Bone Morphogenetic Protein 4 (hrBMP4)” PMID 37563568 ↗ Aug 2023
Route Other “intra- and peritumoral administration by convection enhanced delivery (CED)” PMID 37563568 ↗ Aug 2023