Drugs / Octafibrin
last change Jun 2019 re-read 2 minutes ago

Octafibrin

also known as Fibryga

Protein / enzyme biologic

Developed for
congenital fibrinogen deficiency · congenital afibrinogenemia · acquired coagulation factor deficiency
Investigated by
Octapharma

Trials 3 · a red edge is where a trial was stopped

20142015201620172018201920202021202220232024202520262027
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 21 trial
Phase 2 NCT01575756 Jun 2013 → Jan 2015 congenital afibrinogenemia Octapharma Completed No outcome recorded
Phase 32 trials
Phase 3 NCT02408484 Dec 2015 → Jun 2019 congenital fibrinogen deficiency Octapharma Completed No outcome recorded
Phase 3 NCT02267226 Sep 2014 → Feb 2018 congenital fibrinogen deficiency Octapharma Completed No outcome recorded
Also used as a comparator or background therapy in 1 trial
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 3 NCT03037424 Comparator Feb 2017 → Nov 2018 acquired coagulation factor deficiency University Health Network, Toronto Completed No outcome recorded

Evidence & citations 4 cited values

Every value below carries the sentence it was read from. 5 sources stand behind the page.

FieldValueCited text
Known as Octafibrin ClinicalTrials.gov intervention name — accepted as the source's own label NCT02408484
3

NCT02267226

NCT01575756

NCT03037424

Known as Fibryga “fibrinogen concentrate (Octafibrin/Fibryga; Octapharma) is non-inferior to cryoprecipitate” PMID 29678987 Apr 2018
Modality Protein / enzyme biologic “Plasma derived fibrinogen concentrate” NCT01575756
Route Intravenous “Octafibrin 70 mg/kg intravenously once” NCT01575756