Drugs / Exl-111
last change Feb 2026 re-read 9 days ago

Exl-111

Investigated by
Excellergy Inc.

Trials 1

PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 1 NCT07356713 Jan → Dec 2026 expected allergic disease Excellergy Inc. Recruiting No outcome recorded

News releases announcing trial results or a regulatory action · 1

DateIssuerRelease
2026-02-27 Excellergy Inc. Results Excellergy Presents New Data at 2026 AAAAI Annual Meeting Demonstrating Rapid and Sustained Allergic Effector Cell Control and Announces First Subjects Dosed in Phase 1 DISARM Trial excellergy.com ↗
In primates, Exl-111 achieved rapid and near-complete (>99%) removal of receptor-bound IgE on basophils and induced a ~95% reduction in surface receptor (FcεRI) expression

Evidence & citations 2 cited values

Every value below carries the sentence it was read from. 1 source stands behind the page.

FieldValueCited text
Known as Exl-111 ClinicalTrials.gov intervention name — accepted as the source's own label NCT07356713 ↗
Route Subcutaneous “Exl-111 is administered by subcutaneous injection in a single dose.” NCT07356713 ↗