Drugs / balicatib
last change Jul 2006 re-read 3 minutes ago

balicatib

also known as AAE581

Small molecule targets CTSK via inhibition

Developed for
osteoporosis · osteoarthritis, knee
Investigated by
Novartis Pharmaceuticals

Trials 3

200420052006200720082009201020112012201320142015201620172018201920202021202220232024202520262027
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 2 NCT00170911 Mar → Dec 2005 osteoporosis Novartis Pharmaceuticals Completed No outcome recorded
Phase 2 NCT00371670 Dec 2004 → Jul 2006 osteoarthritis, knee Novartis Pharmaceuticals Completed No outcome recorded
Phase 2 NCT00100607 Feb 2004 → Sep 2005 osteoporosis Novartis Pharmaceuticals Completed No outcome recorded

Evidence & citations 5 cited values

Every value below carries the sentence it was read from. 4 sources stand behind the page.

FieldValueCited text
Known as balicatib ClinicalTrials.gov intervention name — accepted as the source's own label NCT00371670 ↗
Known as AAE581 “balicatib (AAE581)” NCT00371670 ↗
2

NCT00100607 ↗

NCT00170911 ↗

Action Inhibit “AAE581 is a specific inhibitor of the cysteine protease cathepsin K.” NCT00170911 ↗
1

“Cathepsin K inhibitor” CHEMBL371064 ↗

Modality Small molecule — CHEMBL371064 ↗
Target CTSK “Cathepsin K inhibitor” CHEMBL371064 ↗