Drugs / Dicyclomine
Dicyclomine
also known as
Bentyl · Bentyl preservative free · Bentylol · Dicicloverina · Dicyclomine hcl · DICYCLOMINE HYDROCHLORIDE · Dicyclomine hydrochloride (preservative free) · Dicycloverine · +8 more
Small molecule targets CHRM1, CHRM3 via inhibition
Regulatory milestones approvals, filings & regulatory actions · 1 recorded
| Milestone | Jurisdiction | Brand | Indication | Date | Sentence it was read from |
|---|---|---|---|---|---|
| Approved | US (FDA) | BENTYL | — | 1950-05-11 | fda.gov ↗ |
Trials 1 · a red edge is where a trial was stopped
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| Phase | Registry id | Dates | Indication | Sponsor | Status | Outcome |
|---|---|---|---|---|---|---|
| Phase 4 | NCT07461389 | Oct 2025 → Apr 2026 | intestinal motility disease | CMH Lahore Medical College and Institute of Dentistry | Completed | No outcome recorded |
Also used as a comparator or background therapy in 1 trial
| Phase | Registry id | Dates | Indication | Sponsor | Status | Outcome |
|---|---|---|---|---|---|---|
| — | NCT07635394 Background | Apr 2026 overdue | irritable bowel syndrome | Beijing Tiantan Hospital | Recruiting | No outcome recorded |
Evidence & citations 22 cited values
Every value below carries the sentence it was read from. 3 sources stand behind the page.
| Field | Value | Cited text |
|---|---|---|
| Known as | Dicyclomine | “Oral Semithicone 40mg + Dicyclomine 1mg (30min before procedure)” NCT07461389 ↗1“Dicyclomine: 10-20 mg QID” NCT07635394 ↗ |
| Known as | Bentyl | ChEMBL registry synonym — accepted as the source's own label CHEMBL1123 ↗ |
| Known as | Bentyl preservative free | ChEMBL registry synonym — accepted as the source's own label CHEMBL1123 ↗ |
| Known as | Bentylol | ChEMBL registry synonym — accepted as the source's own label CHEMBL1123 ↗ |
| Known as | Dicicloverina | ChEMBL registry synonym — accepted as the source's own label CHEMBL1123 ↗ |
| Known as | Dicyclomine hcl | ChEMBL registry synonym — accepted as the source's own label CHEMBL1123 ↗ |
| Known as | DICYCLOMINE HYDROCHLORIDE | ChEMBL registry synonym — accepted as the source's own label CHEMBL1123 ↗ |
| Known as | Dicyclomine hydrochloride (preservative free) | ChEMBL registry synonym — accepted as the source's own label CHEMBL1123 ↗ |
| Known as | Dicycloverine | ChEMBL registry synonym — accepted as the source's own label CHEMBL1123 ↗ |
| Known as | Dicycloverine hydrochloride | ChEMBL registry synonym — accepted as the source's own label CHEMBL1123 ↗ |
| Known as | Dicymine | ChEMBL registry synonym — accepted as the source's own label CHEMBL1123 ↗ |
| Known as | Kolantyl | ChEMBL registry synonym — accepted as the source's own label CHEMBL1123 ↗ |
| Known as | Kolantyl hydrochloride | ChEMBL registry synonym — accepted as the source's own label CHEMBL1123 ↗ |
| Known as | Merbentyl | ChEMBL registry synonym — accepted as the source's own label CHEMBL1123 ↗ |
| Known as | Merbentyl 20 | ChEMBL registry synonym — accepted as the source's own label CHEMBL1123 ↗ |
| Known as | NSC-404381 | ChEMBL registry synonym — accepted as the source's own label CHEMBL1123 ↗ |
| Known as | Wyovin | ChEMBL registry synonym — accepted as the source's own label CHEMBL1123 ↗ |
| Action | Inhibit | “Muscarinic acetylcholine receptor M3 antagonist” CHEMBL1123 ↗1“Muscarinic acetylcholine receptor M1 antagonist” CHEMBL1123 ↗ |
| Modality | Small molecule | — CHEMBL1123 ↗ |
| Route | Oral | “Oral Semithicone 40mg + Dicyclomine 1mg (30min before procedure)” NCT07461389 ↗ |
| Target | CHRM1 | “Muscarinic acetylcholine receptor M1 antagonist” CHEMBL1123 ↗ |
| Target | CHRM3 | “Muscarinic acetylcholine receptor M3 antagonist” CHEMBL1123 ↗ |