Drugs / calcium hydroxylapatite
calcium hydroxylapatite
Trials 5
| Phase | Registry id | Dates | Indication | Sponsor | Status | Outcome |
|---|---|---|---|---|---|---|
| Phase 12 trials | ||||||
| Phase 1 | NCT05885035 | Jan → Jun 2023 | cellulitis | Kalpna Kay Durairaj, MD, FACS | Completed | No outcome recorded |
| Phase 1 | NCT04176068 | Apr 2019 → Dec 2021 | cutis laxa | University of California, Irvine | Completed | No outcome recorded |
| Phase 42 trials | ||||||
| Phase 4 | NCT05039723 | Sep 2021 → Mar 2022 | — | Main Line Center for Laser Surgery | Completed | No outcome recorded |
| Phase 4 | NCT01225354 | Aug 2010 → Aug 2011 | — | DeNova Research | Completed | No outcome recorded |
| Phase not applicable1 trial | ||||||
| — | NCT07028567 | Jan → Jun 2023 | skin atrophy | Tanta University | Completed | No outcome recorded |
News releases announcing trial results or a regulatory action · 8
| Date | Issuer | Release |
|---|---|---|
| 2026-05-27 | Merz Aesthetics Inc. | Results New Research Shows RADIESSE® Supports Substantial Regeneration of Collagen and Key Extracellular Matrix Proteins merzaesthetics.com ↗
The findings also show that RADIESSE improves signs of solar elastosis, a significant component of sun damage in skin. |
| 2026-04-08 | Merz Aesthetics Inc. | Regulatory Merz Aesthetics Receives FDA Approval for RADIESSE® for the Treatment of Wrinkles in the Décolleté Area merzaesthetics.com ↗
Merz Aesthetics, the world’s largest dedicated medical aesthetics business, announced today the FDA approval for RADIESSE® for the treatment of wrinkles in the décolleté area in patients 22 years of age and older. |
| 2024-02-01 | Merz Aesthetics Inc. | Regulatory Merz Aesthetics receives EU approval for the new indication for Radiesse® as an aesthetic injectable to improve moderate and severe wrinkles in the décolleté area merzaesthetics.com ↗
In the EU, Merz Aesthetics announced today the approval for Radiesse® to treat the décolleté area. |
| 2022-03-31 | Merz Aesthetics Inc. | Results Merz Aesthetics to showcase new data at the 20th Aesthetics & Anti-Aging Medicine World Congress 2022 merzaesthetics.com ↗
Distance between calcium hydroxylapatite microspheres is essential for fibroblast invasion and resulting neocollagenesis. |
| 2020-10-09 | Merz Aesthetics Inc. | Results MERZ AESTHETICS TO PRESENT DATA FROM MEDICAL AESTHETICS PORTFOLIO AT THE AMERICAN SOCIETY OF DERMATOLOGIC SURGERY 2020 ANNUAL MEETING merzaesthetics.com ↗
Calcium hydroxylapatite microspheres provide organization into unorganized collagen networks leading to improvement of skin attractiveness |
| 2020-01-30 | Merz Pharmaceuticals GmbH | Results Merz Aesthetics Presents Data at the IMCAS World Congress 2020 merz.com ↗
Calcium hydroxylapatite microspheres provide organization into unorganized collagen networks leading to improvement of skin attractiveness. |
| 2016-06-07 | Merz Pharmaceuticals GmbH | Regulatory Merz Receives CE Mark for Radiesse® (+) Lidocaine merz.com ↗
Merz Pharma today announced that its dermal filler Radiesse Lidocaine, with integral 0.3% Lidocaine, has received the CE mark and will soon be available to physicians in Europe. |
| 2007-05-07 | Daewoong Pharmaceutical Co. LTD. | Regulatory Radiesse, gained FDA license in the treatment of wrinkles daewoong.co.kr ↗
Filling inject able product, Radiesse (Main ingredients : calcium hydroxyapatite), obtained licenses for the treatment of facial wrinkles such as fortune wrinkles, and giving facial volume to such parts as lip atrophy. |
All press releases naming this drug 12 releases
Evidence & citations 7 cited values
Every value below carries the sentence it was read from. 6 sources stand behind the page.
| Field | Value | Cited text |
|---|---|---|
| Known as | calcium hydroxylapatite | “Calcium hydroxylapatite filler (CaHA; Radiesse) is a synthetic, non-animal derived product composed of minerals that occur naturally in bone and teeth.” PMID 24301235 ↗ Dec 2013 |
| Known as | CaHA | “Calcium hydroxylapatite filler (CaHA; Radiesse) is a synthetic, non-animal derived product composed of minerals that occur naturally in bone and teeth.” PMID 24301235 ↗ Dec 20131“Patients received calcium hydroxylapatite filler (CaHA) (Radiesse®).” NCT07028567 ↗ |
| Known as | calcium hydroxyapatite | “combination, global facial and/or neck treatment with IncobotulinumA (Xeomin), HA (Belotero) and/or calcium hydroxyapatite (Radiesse+, Radiesse Classic).” NCT05039723 ↗ |
| Known as | Radiesse | “Calcium hydroxylapatite filler (CaHA; Radiesse) is a synthetic, non-animal derived product composed of minerals that occur naturally in bone and teeth.” PMID 24301235 ↗ Dec 20132“Patients received calcium hydroxylapatite filler (CaHA) (Radiesse®).” NCT07028567 ↗ “calcium hydroxylapatite (Radiesse) and IFUS (Ulthera)” NCT04176068 ↗ |
| Known as | Radiesse Classic | “calcium hydroxyapatite (Radiesse+, Radiesse Classic)” NCT05039723 ↗ |
| Modality | Other / unclassified | “Calcium hydroxylapatite filler (CaHA; Radiesse) is a synthetic, non-animal derived product composed of minerals that occur naturally in bone and teeth.” PMID 24301235 ↗ Dec 2013 |
| Route | Other | “Subjects will be treated with subdermal injections of CaHA diluted 1:1 with normal saline solution and 1% Lidocaine” NCT05885035 ↗ |