Drugs / pEYS606
last change Jun 2021 re-read 3 minutes ago

pEYS606

Other / unclassified targets TNF via inhibition

Developed for
uveitis
Investigated by
Eyevensys

Trials 1

20172018201920202021202220232024202520262027
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 1/2 NCT03308045 Apr 2017 → Jun 2021 uveitis Eyevensys Completed No outcome recorded

Evidence & citations 5 cited values

Every value below carries the sentence it was read from. 2 sources stand behind the page.

FieldValueCited text
Known as pEYS606 ClinicalTrials.gov intervention name — accepted as the source's own label NCT03308045 ↗
Action Inhibit “encoding a fusion protein consisting of the extracellular domain of the soluble p55 TNF-α receptor linked to the human IgG1 Fc domain (hTNFR-Is/hIgG1 or Protein 6), with high...” PMID 30009894 ↗ Aug 2018
Modality Other / unclassified “non-viral gene therapy using plasmid electrotransfer in the ciliary muscle has been proposed” PMID 30009894 ↗ Aug 2018
Route Other “administered by electrotransfection into the ciliary muscle” NCT03308045 ↗
Target TNF “encoding a fusion protein consisting of the extracellular domain of the soluble p55 TNF-α receptor linked to the human IgG1 Fc domain (hTNFR-Is/hIgG1 or Protein 6), with high...” PMID 30009894 ↗ Aug 2018