Drugs / CARv3-TEAM-E T cells
last change Sep 2026 re-read 3 minutes ago

CARv3-TEAM-E T cells

Cell therapy targets EGFR via depletion

Developed for
glioblastoma
Investigated by
Massachusetts General Hospital

Trials 1

202420252026
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 1 NCT05660369 Mar 2023 → Sep 2026 overdue glioblastoma Massachusetts General Hospital Recruiting No outcome recorded

Evidence & citations 5 cited values

Every value below carries the sentence it was read from. 2 sources stand behind the page.

FieldValueCited text
Known as CARv3-TEAM-E T cells ClinicalTrials.gov intervention name — accepted as the source's own label NCT05660369 ↗
Action Deplete “CARv3-TEAM-E T Cells are made from a person's own collected immune cells (T-Cells) that are genetically changed and then delivered back into the body to try to kill their...” NCT05660369 ↗
Modality Cell therapy “CAR T cells engineered” PMID 38477966 ↗ Mar 2024
Route Other “single intraventricular infusion” PMID 38477966 ↗ Mar 2024
Target EGFR “engineered to target the epidermal growth factor receptor (EGFR) variant III tumor-specific antigen” PMID 38477966 ↗ Mar 2024