Drugs / Tilvestamab
last change Jul 2025 re-read 3 minutes ago

Tilvestamab

also known as BGB149

Monoclonal antibody targets AXL

Developed for
ovarian neoplasm
Investigated by
BerGenBio ASA

Trials 2

20192020202120222023202420252026
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 01 trial
Phase 0 NCT03795142 Dec 2018 → Oct 2019 — BerGenBio ASA Completed No outcome recorded
Phase 11 trial
Phase 1 NCT04893551 Feb 2021 → Jun 2022 ovarian neoplasm BerGenBio ASA Terminated No outcome recorded Stop: Business

Evidence & citations 5 cited values

Every value below carries the sentence it was read from. 4 sources stand behind the page.

FieldValueCited text
Known as Tilvestamab ClinicalTrials.gov intervention name — accepted as the source's own label NCT04893551 ↗
Known as BGB149 ClinicalTrials.gov intervention name — accepted as the source's own label NCT03795142 ↗
Modality Monoclonal antibody “Tilvestamab is a highly selective humanised immunoglobulin G1 anti-AXL monoclonal antibody.” PMID 40696160 ↗ Jul 2025
1

CHEMBL4594530 ↗

Route Intravenous “after single IV doses in healthy male and female subjects.” NCT03795142 ↗
Target AXL “Tilvestamab is a highly selective humanised immunoglobulin G1 anti-AXL monoclonal antibody.” PMID 40696160 ↗ Jul 2025