Drugs / BPX-601
last change Jul 2026 re-read 2 minutes ago

BPX-601

Cell therapy targets PSCA via depletion

Developed for
castration-resistant prostate carcinoma · metastatic prostate carcinoma · prostate cancer
Investigated by
Regeneron Pharmaceuticals

Trials 2 · a red edge is where a trial was stopped

20172018201920202021202220232024202520262027202820292030
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 1 NCT07543055 Jul 2026 → Feb 2030 expected prostate cancer Regeneron Pharmaceuticals Recruiting No outcome recorded
Phase 1 NCT02744287 Nov 2016 → Mar 2023 castration-resistant prostate carcinoma, metastatic prostate carcinoma Regeneron Pharmaceuticals Terminated No outcome recorded

Evidence & citations 5 cited values

Every value below carries the sentence it was read from. 2 sources stand behind the page.

FieldValueCited text
Known as BPX-601 ClinicalTrials.gov intervention name — accepted as the source's own label NCT02744287
1

NCT07543055

Action Deplete “How well BPX-601 may work to destroy prostate cancer” NCT07543055
Modality Cell therapy “Autologous T cells genetically modified with retrovirus vector containing PSCA-specific CAR and an inducible MyD88/Cluster Designation (CD)40 (iMC) co-stimulatory domain” NCT02744287
Route Intravenous “Participants with advanced prostate cancer will receive an intravenous infusion of BPX-601” NCT02744287
Target PSCA “Participants' T cells are modified to recognize and target the PSCA tumor marker on cancer cells.” NCT02744287