Drugs / antazoline
antazoline
also known as
Antaz hcl · Antaz sulf · Antazolina · Antazoline hcl · ANTAZOLINE HYDROCHLORIDE · ANTAZOLINE PHOSPHATE · Antazoline phosphate component of vasocon-a · Atazoline · +2 more
Small molecule targets HRH1 via inhibition
Regulatory milestones approvals, filings & regulatory actions · 1 recorded
| Milestone | Jurisdiction | Brand | Indication | Date | Sentence it was read from |
|---|---|---|---|---|---|
| Approved | US (FDA) | VASOCON-A | — | 1990-04-30 | fda.gov ↗ |
Trials 2 · a red edge is where a trial was stopped
| Phase | Registry id | Dates | Indication | Sponsor | Status | Outcome |
|---|---|---|---|---|---|---|
| Phase 4 | NCT05720572 | Sep 2019 → Sep 2025 | atrial fibrillation | Centre of Postgraduate Medical Education | Unknown | No outcome recorded |
| Phase 4 | NCT01527279 | Nov 2012 → Jan 2015 | paroxysmal atrial fibrillation | National Institute of Cardiology, Warsaw, Poland | Completed | No outcome recorded |
Also used as a comparator or background therapy in 1 trial
| Phase | Registry id | Dates | Indication | Sponsor | Status | Outcome |
|---|---|---|---|---|---|---|
| Phase 3 | NCT01380678 Comparator | Jan 2009 → Dec 2012 | pterygium | Khon Kaen University | Unknown | No outcome recorded |
Evidence & citations 15 cited values
Every value below carries the sentence it was read from. 4 sources stand behind the page.
| Field | Value | Cited text |
|---|---|---|
| Known as | antazoline | “combination of topical antazoline HCl 0.05% and tetrahydrozoline HCl 0.04%” NCT01380678 ↗ |
| Known as | Antaz hcl | ChEMBL registry synonym — accepted as the source's own label CHEMBL1305 ↗ |
| Known as | Antaz sulf | ChEMBL registry synonym — accepted as the source's own label CHEMBL1305 ↗ |
| Known as | Antazolina | ChEMBL registry synonym — accepted as the source's own label CHEMBL1305 ↗ |
| Known as | Antazoline hcl | ChEMBL registry synonym — accepted as the source's own label CHEMBL1305 ↗ |
| Known as | ANTAZOLINE HYDROCHLORIDE | ChEMBL registry synonym — accepted as the source's own label CHEMBL1305 ↗ |
| Known as | ANTAZOLINE PHOSPHATE | ChEMBL registry synonym — accepted as the source's own label CHEMBL1305 ↗ |
| Known as | Antazoline phosphate component of vasocon-a | ChEMBL registry synonym — accepted as the source's own label CHEMBL1305 ↗ |
| Known as | Atazoline | ChEMBL registry synonym — accepted as the source's own label CHEMBL1305 ↗ |
| Known as | NSC-755865 | ChEMBL registry synonym — accepted as the source's own label CHEMBL1305 ↗ |
| Known as | Vasocon-a | ChEMBL registry synonym — accepted as the source's own label CHEMBL1305 ↗ |
| Action | Inhibit | “Histamine H1 receptor antagonist” CHEMBL1305 ↗ |
| Modality | Small molecule | — CHEMBL1305 ↗ |
| Route | Topical | “combination of topical antazoline HCl 0.05% and tetrahydrozoline HCl 0.04%” NCT01380678 ↗ |
| Target | HRH1 | “Histamine H1 receptor antagonist” CHEMBL1305 ↗ |