Drugs / FALBIKITUG
last change Jun 2026 re-read 9 days ago

FALBIKITUG

also known as AZD0171 · MSC-1

Monoclonal antibody targets LIF

Developed for
non-small cell lung carcinoma · malignant pancreatic neoplasm · ovarian cancer
Investigated by
AstraZeneca · Parexel

Trials 3

201920202021202220232024202520262027202820292030
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 11 trial
Phase 1 NCT03490669 May 2018 → Sep 2019 malignant pancreatic neoplasm, non-small cell lung carcinoma, ovarian cancer AstraZeneca Completed No outcome recorded
Phase 22 trials
Phase 2 NCT05061550 Apr 2022 → May 2030 expected non-small cell lung carcinoma AstraZeneca Recruiting No outcome recorded
Phase 2 NCT04999969 Dec 2021 → Oct 2024 overdue — AstraZeneca Active not recruiting No outcome recorded

News releases announcing trial results or a regulatory action · 1

DateIssuerRelease
2022-03-28 AstraZeneca Results AstraZeneca aims to transform the oncology treatment landscape with diverse early pipeline and novel combinations at AACR astrazeneca.com ↗
AZD0171 (anti-LIF) combines productively with chemotherapy and anti-PD-L1 in mouse models of cancer

All press releases naming this drug 1 release

DateIssuerRelease

Evidence & citations 6 cited values

Every value below carries the sentence it was read from. 4 sources stand behind the page.

FieldValueCited text
Known as FALBIKITUG ChEMBL registry synonym — accepted as the source's own label CHEMBL5315010 ↗
Known as AZD0171 ClinicalTrials.gov intervention name — accepted as the source's own label NCT04999969 ↗
1

NCT05061550 ↗

Known as MSC-1 ClinicalTrials.gov intervention name — accepted as the source's own label NCT03490669 ↗
Modality Monoclonal antibody “humanized monoclonal antibody (IgG1)” NCT03490669 ↗
1

CHEMBL5315010 ↗

Route Intravenous “MSC-1 will be administered intravenously (IV)” NCT03490669 ↗
Target LIF “binds to the immunosuppressive human cytokine Leukemia Inhibitory Factor (LIF)” NCT03490669 ↗