Drugs / BMS-986156
last change Apr 2025 re-read 3 minutes ago

BMS-986156

Monoclonal antibody targets TNFRSF18 via activation

Developed for
cancer · carcinoma of liver and intrahepatic biliary tract · lung carcinoma · metastatic malignant neoplasm
Investigated by
Bristol-Myers Squibb · M.D. Anderson Cancer Center

Trials 2

201620172018201920202021202220232024202520262027
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 1/2 NCT04021043 Aug 2019 → Apr 2025 carcinoma of liver and intrahepatic biliary tract, lung carcinoma, metastatic malignant neoplasm M.D. Anderson Cancer Center Completed No outcome recorded
Phase 1/2 NCT02598960 Oct 2015 → Dec 2019 cancer Bristol-Myers Squibb Completed No outcome recorded

Evidence & citations 5 cited values

Every value below carries the sentence it was read from. 4 sources stand behind the page.

FieldValueCited text
Known as BMS-986156 ClinicalTrials.gov intervention name — accepted as the source's own label NCT04021043 ↗
1

NCT02598960 ↗

Action Activate “BMS-986156 is a fully agonistic human immunoglobulin G subclass 1 monoclonal antibody targeting GITR.” PMID 36863094 ↗ Feb 2023
Modality Monoclonal antibody “BMS-986156 is a fully agonistic human immunoglobulin G subclass 1 monoclonal antibody targeting GITR.” PMID 36863094 ↗ Feb 2023
Route Intravenous “The protein agonist BMS-986156 was administered intravenously at a dose of 10, 30, 100, 240, or 800 mg every 2 weeks as monotherapy” PMID 31697308 ↗ Jan 2020
Target TNFRSF18 “TNFRSF18 Agonist BMS-986156” NCT04021043 ↗