Drugs / Benzathine Penicillin G
Benzathine Penicillin G
also known as
BPG · Benzathine Benzyl Penicillin G · benzathine benzylpenicillin · penicillin G benzathine
Trials 4 · a red edge is where a trial was stopped
| Phase | Registry id | Dates | Indication | Sponsor | Status | Outcome |
|---|---|---|---|---|---|---|
| Phase 21 trial | ||||||
| Phase 2 | NCT03346525 | Jun 2018 → Nov 2020 | rheumatic heart disease | Children's National Research Institute | Unknown | No outcome recorded |
| Phase 43 trials | ||||||
| Phase 4 | NCT02857959 | Aug 2016 → Jun 2020 | syphilis | Jun Li | Unknown | No outcome recorded |
| Phase 4 | NCT02871505 | Aug 2016 → Aug 2020 | syphilis | Peking Union Medical College Hospital | Unknown | No outcome recorded |
| Phase 4 | NCT02611765 | Sep 2008 → Apr 2012 | syphilis | Baylor College of Medicine | Completed | No outcome recorded |
Also used as a comparator or background therapy in 10 trials
| Phase | Registry id | Dates | Indication | Sponsor | Status | Outcome |
|---|---|---|---|---|---|---|
| Phase 25 trials | ||||||
| Phase 2 | NCT06921213 Comparator | May 2026 → Mar 2027 expected | congenital syphilis | London School of Hygiene and Tropical Medicine | Recruiting | No outcome recorded |
| Phase 2 | NCT05548426 Comparator | Sep 2023 → Aug 2026 overdue | syphilis | University of Southern California | Active not recruiting | No outcome recorded |
| Phase 2 | NCT05693545 Comparator | Sep 2023 → Mar 2027 expected | rheumatic heart disease | Children's Hospital Medical Center, Cincinnati | Active not recruiting | No outcome recorded |
| Phase 2 | NCT03660488 Comparator | Sep 2018 → Jan 2021 | syphilis | University of California, Los Angeles | Completed | No outcome recorded |
| Phase 2 | NCT01769027 Comparator | Jun → Dec 2013 | — | CNS Onlus | Withdrawn | No outcome recorded |
| Phase 32 trials | ||||||
| Phase 3 | NCT05894954 Background | Jul 2023 → Oct 2025 | cognitive impairment with or without cerebellar ataxia, dementia | Alzheimer's Prevention and Reversal Project, Inc. | Completed | No outcome recorded |
| Phase 3 | NCT05069974 Comparator | Oct 2021 → Apr 2026 | latent early syphilis, primary syphilis, secondary syphilis | Fight AIDS and Infectious Diseases Foundation | Completed | No outcome recorded |
| Phase 42 trials | ||||||
| Phase 4 | NCT05980871 Comparator | Mar 2023 → Jul 2025 | syphilis | National Taiwan University Hospital | Terminated | No outcome recorded |
| Phase 4 | NCT06907316 Comparator | Jul 2021 → Aug 2024 | latent early syphilis | Bulovka Hospital | Terminated | No outcome recorded |
| Phase not applicable1 trial | ||||||
| — | NCT06069141 Comparator | Jan 2024 → Dec 2027 expected | latent early syphilis | National Taiwan University Hospital | Recruiting | No outcome recorded |
Evidence & citations 6 cited values
Every value below carries the sentence it was read from. 17 sources stand behind the page.
| Field | Value | Cited text |
|---|---|---|
| Known as | Benzathine Penicillin G | “Bacterial or Viral infection treatment may include: Doxycycline, Minocycline, Nitazoxanide, Hydroxychloroquine, Rifampin, Dapsone, Azithromycin, Tetracycline, Benzathine...” NCT05894954 ↗13“The Trep-AB clinical trial will test the efficacy of an investigational neuropenetrative drug, Linezolid (LZD), compared to standard treatment, Benzathine penicillin G (BPG),...” NCT05069974 ↗ “Standard of care benzathine penicillin G, one intramuscular injection, 2.4MU” NCT05548426 ↗ “benzathine penicillin G 2.4 MIU single dose intramuscularly” NCT06907316 ↗ “benzathine penicillin G 1.200.000 U every 3 weeks” NCT01769027 ↗ |
| Known as | Benzathine Benzyl Penicillin G | “to Benzathine Benzyl Penicillin G (BPG arm, every-28-day intramuscular penicillin)” PMID 38797460 ↗ May 2024 |
| Known as | benzathine benzylpenicillin | “Participants were randomly assigned to receive either injections of penicillin G benzathine (also known as benzathine benzylpenicillin) every 4 weeks for 2 years or no prophylaxis.” PMID 34767321 ↗ Nov 2021 |
| Known as | BPG | “The Trep-AB clinical trial will test the efficacy of an investigational neuropenetrative drug, Linezolid (LZD), compared to standard treatment, Benzathine penicillin G (BPG),...” NCT05069974 ↗2“Currently a single dose of 2.4 million units of intramuscular benzathine penicillin G (BPG) is recommended for the treatment of early syphilis.” PMID 28200045 ↗ Mar 2017 “single-dose benzathine penicillin G (BPG) (2.4 MU intramuscularly once) plus doxycycline (100 mg orally twice daily for 7 days)” NCT06069141 ↗ |
| Known as | penicillin G benzathine | “Participants were randomly assigned to receive either injections of penicillin G benzathine (also known as benzathine benzylpenicillin) every 4 weeks for 2 years or no prophylaxis.” PMID 34767321 ↗ Nov 2021 |
| Route | Intramuscular | “Three doses of intramuscular 2.4 million units of benzathine penicillin G administered weekly” NCT02611765 ↗ |