Drugs / X-82

Trials 3

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PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 11 trial
Phase 1 NCT02146222 Sep 2014 → Dec 2016 cancer of unknown primary site University of Wisconsin, Madison Completed No outcome recorded
Phase 1/21 trial
Phase 1/2 NCT01674569 Oct 2012 → Feb 2015 wet macular degeneration Tyrogenex Completed No outcome recorded
Phase 21 trial
Phase 2 NCT02348359 Mar 2015 → Dec 2017 age related macular degeneration 10, wet macular degeneration Tyrogenex Terminated No outcome recorded

Evidence & citations 4 cited values

Every value below carries the sentence it was read from. 4 sources stand behind the page.

FieldValueCited text
Known as X-82 ClinicalTrials.gov intervention name — accepted as the source's own label NCT02146222 ↗
2

NCT02348359 ↗

NCT01674569 ↗

Action Inhibit “VEGFR/PDGFR dual kinase inhibitor X-82 may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth.” NCT02146222 ↗
Modality Small molecule “X-82 is an oral tyrosine kinase inhibitor active against vascular endothelial growth factor (VEGF) and platelet-derived growth factor.” PMID 28570723 ↗ Jul 2017
Route Oral “Participants received oral X-82 for 24 weeks” PMID 28570723 ↗ Jul 2017