Drugs / DOTAP:Chol-fus1
last change Apr 2012 re-read 3 minutes ago

DOTAP:Chol-fus1

also known as DOTAP:chol-TUSC2

targets TUSC2 via restoration

Developed for
lung cancer
Investigated by
M.D. Anderson Cancer Center · National Cancer Institute (NCI)

Trials 1

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PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 1 NCT00059605 Mar 2003 → Apr 2011 lung cancer M.D. Anderson Cancer Center Completed No outcome recorded

Evidence & citations 5 cited values

Every value below carries the sentence it was read from. 2 sources stand behind the page.

FieldValueCited text
Known as DOTAP:Chol-fus1 ClinicalTrials.gov intervention name — accepted as the source's own label NCT00059605 ↗
Known as DOTAP:chol-TUSC2 “Patients with recurrent and/or metastatic lung cancer previously treated with platinum-based chemotherapy were treated with escalating doses of intravenous...” PMID 22558101 ↗ Apr 2012
Action Restore “The idea is to try to replace this gene in lung cancer cells.” NCT00059605 ↗
Route Intravenous “administered intravenously” NCT00059605 ↗
Target TUSC2 “encapsulating a TUSC2 expression plasmid” PMID 22558101 ↗ Apr 2012