Drugs / SPC5001
last change Oct 2015 re-read 3 minutes ago

SPC5001

Antisense oligonucleotide targets PCSK9 via inhibition

Developed for
familial hypercholesterolemia
Investigated by
Santaris Pharma A/S

Trials 1

20112012201320142015201620172018201920202021202220232024202520262027
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 1 NCT01350960 May → Oct 2011 familial hypercholesterolemia Santaris Pharma A/S Terminated No outcome recorded

Evidence & citations 5 cited values

Every value below carries the sentence it was read from. 2 sources stand behind the page.

FieldValueCited text
Known as SPC5001 ClinicalTrials.gov intervention name — accepted as the source's own label NCT01350960 ↗
Action Inhibit “SPC5001 treatment dose-dependently inhibited PCSK9” PMID 26261033 ↗ Oct 2015
Modality Antisense oligonucleotide “SPC5001, a locked nucleic acid antisense inhibitor of PCSK9.” PMID 26261033 ↗ Oct 2015
Route Subcutaneous “three weekly subcutaneous administrations of SPC5001” PMID 26261033 ↗ Oct 2015
Target PCSK9 “target protein PCSK9” PMID 26261033 ↗ Oct 2015