Drugs / TAK-928
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TAK-928

Monoclonal antibody

Developed for
non-small cell lung carcinoma
Investigated by
Innovent Biologics (Suzhou) Co. Ltd. · Takeda

Trials 1

202620272028
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 3 NCT07217301 Nov 2025 → Nov 2028 expected non-small cell lung carcinoma Takeda Recruiting No outcome recorded

News releases announcing trial results or a regulatory action · 5

DateIssuerRelease
2026-06-01 Innovent Biologics (Suzhou) Co. Ltd. Results 2026 ASCO | Innovent Presents Long-Term Follow-up Results from the PoC Study of IBI363 (TAK-928) (PD-1/IL-2α-bias bispecific fusion protein), Showing Robust Survival Benefits in Advanced Immunotherapy-Resistant Non-Small Cell Lung Cancer innoventbio.com ↗
After long-term follow-up, IBI363 monotherapy demonstrated strong overall survival (OS) with a long tail effect in IO-resistant squamous NSCLC and adenoNSCLC
2026-06-01 Innovent Biologics (Suzhou) Co. Ltd. Results 2026 ASCO | Innovent Presents Preliminary PoC Data of IBI363 (TAK-928) PD-1/IL-2α-bias bispecific fusion protein) in First-line Advanced NSCLC innoventbio.com ↗
2026-05-22 Innovent Biologics (Suzhou) Co. Ltd. Results 2026 ASCO Abstract Highlights | Innovent Announces Preliminary PoC data of IBI363 in Combination with Chemotherapy as First-line Treatment for Advanced NSCLC, Showing Encouraging Efficacy Signals and Favorable Safety innoventbio.com ↗
The preliminary results showed that IBI363 combined with PDC demonstrated encouraging efficacy signals in the first-line treatment of NSCLC with PD-L1 negative or low expression.
2026-05-22 Innovent Biologics (Suzhou) Co. Ltd. Results 2026 ASCO Abstract Highlights: Innovent Biologics' IBI363 (PD-1/IL-2α-bias bispecific fusion protein) Demonstrates Robust Survival Benefits in Long-Term Follow-up of PoC Study in Advanced Immunotherapy-Resistant Non-Small Cell Lung Cancer innoventbio.com ↗
Updated data from this PoC study conducted in China, showed that after extended follow-up, IBI363 continued to demonstrate a manageable long-term safety profile in IO-resistant NSCLC.
2026-05-11 Innovent Biologics (Suzhou) Co. Ltd. Regulatory Innovent Announces IBI363 (PD-1/IL-2α-bias Bispecific Fusion Protein) Received Third NMPA Breakthrough Therapy Designation for MSS/pMMR Metastatic Colorectal Cancer innoventbio.com ↗

All press releases naming this drug 7 releases

DateIssuerRelease

Evidence & citations 3 cited values

Every value below carries the sentence it was read from. 1 source stands behind the page.

FieldValueCited text
Known as TAK-928 ClinicalTrials.gov intervention name — accepted as the source's own label NCT07217301 ↗
Modality Monoclonal antibody “TAK-928 is a first-in-class bispecific monoclonal antibody (mAb)” NCT07217301 ↗
Route Intravenous “TAK-928 will be administered by IV infusion.” NCT07217301 ↗