Drugs / HIL-214
last change Dec 2024 re-read 2 minutes ago

HIL-214

also known as TAK-214

Vaccine

Developed for
gastroenteritis · norovirus infectious disease
Investigated by
HilleVax · Takeda

Trials 6 · a red edge is where a trial was stopped

PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 11 trial
Phase 1 NCT06007781 Aug 2023 → May 2024 gastroenteritis HilleVax Completed No outcome recorded
Phase 23 trials
Phase 2 NCT05972733 Aug 2023 gastroenteritis HilleVax Completed No outcome recorded
Phase 2 NCT02153112 Jun 2015 → Jun 2018 norovirus infectious disease Takeda Completed No outcome recorded
Phase 2 NCT02475278 Feb → Apr 2015 norovirus infectious disease Takeda Completed No outcome recorded
Phase 2/32 trials
Phase 2/3 NCT05836012 Jun 2023 → Jan 2024 gastroenteritis HilleVax Completed No outcome recorded
Phase 2/3 NCT05281094 Apr 2022 → Dec 2023 gastroenteritis HilleVax Terminated No outcome recorded

Evidence & citations 4 cited values

Every value below carries the sentence it was read from. 6 sources stand behind the page.

FieldValueCited text
Known as HIL-214 “We conducted a dose-finding phase 2 study of the HilleVax bivalent virus-like particle (VLP) vaccine candidate (HIL-214) in two cohorts of children, 6-≤12 months and 1-≤4 years...” PMID 37140558 May 2023
5

“Serum samples collected during the evaluation of an investigational norovirus vaccine (HIL-214 [formerly TAK-214]) were assayed” PMID 38864524 Dec 2024

NCT05836012

NCT06007781

NCT05281094

NCT05972733

Known as TAK-214 “Serum samples collected during the evaluation of an investigational norovirus vaccine (HIL-214 [formerly TAK-214]) were assayed” PMID 38864524 Dec 2024
Modality Vaccine “HilleVax bivalent virus-like particle (VLP) vaccine candidate (HIL-214)” PMID 37140558 May 2023
Route Intramuscular “received intramuscular injections of four different HIL-214 formulations” PMID 37140558 May 2023