Drugs / RG7652
last change Mar 2017 re-read 3 minutes ago

RG7652

also known as MPSK3169A

Monoclonal antibody targets PCSK9 via inhibition

Developed for
coronary artery disorder
Investigated by
Genentech, Inc.

Trials 1

2012201320142015201620172018201920202021202220232024202520262027
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 2 NCT01609140 May 2012 → May 2013 coronary artery disorder Genentech, Inc. Completed Met primary

Evidence & citations 6 cited values

Every value below carries the sentence it was read from. 2 sources stand behind the page.

FieldValueCited text
Known as RG7652 “RG7652 (MPSK3169A), a fully human immunoglobulin G1 (IgG1) monoclonal antibody directed against proprotein convertase subtilisin/kexin type 9 (PCSK9), blocks the interaction...” PMID 28343601 ↗ Mar 2017
Known as MPSK3169A ClinicalTrials.gov intervention name — accepted as the source's own label NCT01609140 ↗
Action Inhibit “blocks the interaction between PCSK9 and low-density lipoprotein (LDL) receptor” PMID 28343601 ↗ Mar 2017
Modality Monoclonal antibody “RG7652 (MPSK3169A), a fully human immunoglobulin G1 (IgG1) monoclonal antibody” PMID 28343601 ↗ Mar 2017
Route Subcutaneous “given as subcutaneous (SC) injections over a 24-week period” NCT01609140 ↗
Target PCSK9 “directed against proprotein convertase subtilisin/kexin type 9 (PCSK9)” PMID 28343601 ↗ Mar 2017