Drugs / pavurutamab
last change Jul 2026 re-read 2 minutes ago

pavurutamab

Protein / enzyme biologic

Developed for
refractory plasma cell neoplasm
Investigated by
Amgen

Trials 2 · a red edge is where a trial was stopped

201820192020202120222023202420252026
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 1 NCT04998747 Aug 2023 → Aug 2025 refractory plasma cell neoplasm Amgen Withdrawn No outcome recorded
Phase 1 NCT03287908 Nov 2017 → Jun 2023 refractory plasma cell neoplasm Amgen Terminated No outcome recorded
Also used as a comparator or background therapy in 1 trial
PhaseRegistry idDatesIndicationSponsorStatusOutcome
NCT05256446 Background Amgen No longer available No outcome recorded

Press releases naming this drug 1 release

DateIssuerRelease
2020-12-05 Amgen Amgen To Present First Clinical Data For BCMA-Targeted Half-Life Extended BiTE® Therapy AMG 701 At ASH 2020 amgen.com

Evidence & citations 5 cited values

Every value below carries the sentence it was read from. 6 sources stand behind the page.

FieldValueCited text
Known as pavurutamab “The B-cell maturation antigen (BCMA)-targeting bispecific T-cell engager pavurutamab (AMG 701) directs the cytotoxic T-cell response toward multiple myeloma (MM) cells.” PMID 41950113 Jul 2026
Known as AMG 701 ClinicalTrials.gov intervention name — accepted as the source's own label NCT05256446
2

NCT03287908

NCT04998747

Known as Anti-bcma x anti-cd3 bite amg 701 ChEMBL registry synonym — accepted as the source's own label CHEMBL4650255
Modality Protein / enzyme biologic “bispecific T-cell engager molecule AMG 701” PMID 32898244 Sep 2020
Route Intravenous “Subjects will receive IV infusions of AMG 701.” NCT03287908