Drugs / QBECO
last change Feb 2025 re-read 3 minutes ago

QBECO

Other / unclassified

Developed for
Crohn disease
Investigated by
Qu Biologics Inc.

Trials 1

201320142015201620172018201920202021202220232024202520262027
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 1/2 NCT01809275 Mar 2013 → Feb 2016 Crohn disease Qu Biologics Inc. Completed No outcome recorded

News releases announcing trial results or a regulatory action · 4

DateIssuerRelease
2025-02-10 Qu Biologics Inc. Results Qu Biologics’ Immunomodulator Clears Senescence qubiologics.com ↗
Qu’s QBECO immunomodulator substantially reduced the most widely used biomarker of cellular senescence in the liver of mice with fatty liver disease.
2025-01-06 Qu Biologics Inc. Results Qu Biologics’ Immunomodulator Improves Fatty Liver Disease qubiologics.com ↗
In a series of studies at McMaster, Dr. Schertzer’s research group demonstrated that treatment with QBECO SSI resulted in a marked reduction in liver fat, inflammation, and fibrosis in fatty liver disease.
2024-12-16 Qu Biologics Inc. Results Qu Biologics’ Site Specific Immunomodulator Enables CAR T-cell Cancer Efficacy in Solid Tumor qubiologics.com ↗
In this experimental study, scientists demonstrated that combining QBECO SSI with CAR T-cell therapy significantly improved survival rates compared to CAR T-cell therapy alone, achieving an impressive 80% survival rate after 31 days of treatment.
2021-07-13 Qu Biologics Inc. Results Qu Biologics’ Phase 2 RESTORE trial data presented at 2021 European Crohn’s and Colitis Congress qubiologics.com ↗
The RESTORE study, presented at ECCO 2021, demonstrated both symptom improvement/remission and endoscopic response.

Evidence & citations 4 cited values

Every value below carries the sentence it was read from. 2 sources stand behind the page.

FieldValueCited text
Known as QBECO ClinicalTrials.gov intervention name — accepted as the source's own label NCT01809275 ↗
Action Restore “aims to restore rather than suppress immune function in CD” PMID 31380382 ↗ Jul 2019
Modality Other / unclassified “a novel microbial-derived immunotherapy” PMID 31380382 ↗ Jul 2019
Route Subcutaneous “administered subcutaneously” NCT01809275 ↗