Drugs / hCAR-T
last change Dec 2023 re-read 3 minutes ago

hCAR-T

Cell therapy targets CD19 via depletion

Developed for
leukemia · lymphoma
Investigated by
Southwest Hospital, China

Trials 1

2015201620172018201920202021202220232024202520262027
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 1/2 NCT02349698 Dec 2014 → Dec 2022 leukemia, lymphoma Southwest Hospital, China Unknown No outcome recorded

Evidence & citations 4 cited values

Every value below carries the sentence it was read from. 2 sources stand behind the page.

FieldValueCited text
Known as hCAR-T “In this study, we developed a humanized anti-CD19 scFv CAR-T (hCAR-T) to treat patients with relapsed/refractory acute lymphoblastic leukemia (r/r ALL).” PMID 31732519 ↗ Nov 2019
Action Deplete “Preclinical studies have demonstrated effective killing of CD19 target cells.” NCT02349698 ↗
Modality Cell therapy “T cells modified with hCAR” PMID 31732519 ↗ Nov 2019
Target CD19 “T cells modified with CD19 targeted chimeric antigen receptor.” NCT02349698 ↗