Drugs / GSK2879552
last change Jan 2018 re-read 9 days ago

GSK2879552

Small molecule

Developed for
acute myeloid leukemia · myelodysplastic syndrome · small cell carcinoma
Investigated by
GlaxoSmithKline · Parexel

Trials 3

20142015201620172018201920202021202220232024202520262027
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 12 trials
Phase 1 NCT02177812 Aug 2014 → Dec 2017 acute myeloid leukemia GlaxoSmithKline Terminated No outcome recorded
Phase 1 NCT02034123 Feb 2014 → Apr 2017 small cell carcinoma GlaxoSmithKline Terminated No outcome recorded
Phase 1/21 trial
Phase 1/2 NCT02929498 Jul 2017 → Jan 2018 myelodysplastic syndrome GlaxoSmithKline Terminated No outcome recorded

News releases announcing trial results or a regulatory action · 1

DateIssuerRelease
2015-11-03 GlaxoSmithKline Results GSK profiles innovative R&D portfolio to investors gsk.com ↗
The phase I studies have shown an early signal of significant progression-free survival for some patients with SCLC.

All press releases naming this drug 1 release

DateIssuerRelease

Evidence & citations 4 cited values

Every value below carries the sentence it was read from. 4 sources stand behind the page.

FieldValueCited text
Known as GSK2879552 ClinicalTrials.gov intervention name — accepted as the source's own label NCT02177812 ↗
2

NCT02034123 ↗

NCT02929498 ↗

Action Inhibit “lysine specific demethylase 1 (LSD1) inhibitor GSK2879552” NCT02177812 ↗
Modality Small molecule — CHEMBL3786182 ↗
Route Oral “Subjects will receive GSK2879552orally with approximately 200 milliliter (mL) of water.” NCT02034123 ↗