Drugs / Gene-modified CD34+ cells
last change Mar 2025 re-read 2 minutes ago

Gene-modified CD34+ cells

Cell therapy

Developed for
sickle cell disease
Investigated by
National Heart, Lung, and Blood Institute (NHLBI) · St. Jude Children's Research Hospital

Trials 1 · a red edge is where a trial was stopped

20262027202820292030
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 1 NCT06506461 Mar 2025 → Dec 2029 expected sickle cell disease St. Jude Children's Research Hospital Recruiting No outcome recorded

Evidence & citations 3 cited values

Every value below carries the sentence it was read from. 1 source stands behind the page.

FieldValueCited text
Known as Gene-modified CD34+ cells ClinicalTrials.gov intervention name — accepted as the source's own label NCT06506461
Modality Cell therapy “autologous infusion of clustered regularly interspaced palindromic repeats (CRISPR)/ CRISPR associated protein (Cas9)-edited CD34+ hematopoietic stem and progenitor cells (HSPCs)” NCT06506461
Route Intravenous “Given Intravenous (IV)” NCT06506461