Drugs / PRX-03140
last change Jun 2013 re-read 2 minutes ago

PRX-03140

Small molecule targets HTR4 via activation

Developed for
Alzheimer disease · post-traumatic stress disorder
Investigated by
Epix Pharmaceuticals, Inc. · Alachua Government Services, Inc.

Trials 4 · a red edge is where a trial was stopped

200720082009201020112012201320142015201620172018201920202021202220232024202520262027
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 23 trials
Phase 2 NCT00693004 May 2008 → Jan 2010 Alzheimer disease Epix Pharmaceuticals, Inc. Terminated No outcome recorded
Phase 2 NCT00672945 Apr 2008 → Jan 2010 Alzheimer disease Epix Pharmaceuticals, Inc. Terminated No outcome recorded
Phase 2 NCT00384423 Oct 2006 → Oct 2007 Alzheimer disease Epix Pharmaceuticals, Inc. Completed No outcome recorded
Phase not applicable1 trial
NCT01492699 Jun 2012 → Jun 2013 post-traumatic stress disorder Alachua Government Services, Inc. Completed No outcome recorded

Evidence & citations 5 cited values

Every value below carries the sentence it was read from. 5 sources stand behind the page.

FieldValueCited text
Known as PRX-03140 ClinicalTrials.gov intervention name — accepted as the source's own label NCT00384423
3

NCT00672945

NCT01492699

NCT00693004

Action Activate “Serotonin 4 (5-HT4) receptor partial agonist” CHEMBL3306918
Modality Small molecule CHEMBL3306918
Route Oral “PRX-03140 administered orally once daily for 14 days” NCT00384423
Target HTR4 “Serotonin 4 (5-HT4) receptor partial agonist” CHEMBL3306918