Drugs / Levoketoconazole
last change Dec 2022 re-read 2 minutes ago

Levoketoconazole

also known as DIO-902 · 2S,4R-ketoconazole
Developed for
endogenous Cushing syndrome · type 2 diabetes mellitus
Investigated by
Cortendo AB · DiObex

Regulatory milestones approvals, filings & regulatory actions · 1 recorded

MilestoneJurisdictionBrandIndicationDateSentence it was read from
Approved US (FDA) RECORLEV 2021-12-30 fda.gov

Trials 8 · a red edge is where a trial was stopped

PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 13 trials
Phase 1 NCT04212000 Dec 2019 → Jan 2020 Cortendo AB Completed No outcome recorded
Phase 1 NCT03880825 Mar → May 2019 Cortendo AB Completed No outcome recorded
Phase 1 NCT03768388 Nov → Dec 2018 Cortendo AB Completed No outcome recorded
Phase 21 trial
Phase 2 NCT00494663 Jul 2007 → Mar 2008 type 2 diabetes mellitus DiObex Terminated No outcome recorded
Phase 2/31 trial
Phase 2/3 NCT00622089 Jan → Dec 2008 type 2 diabetes mellitus DiObex Terminated No outcome recorded
Phase 33 trials
Phase 3 NCT03621280 Jan 2019 → Dec 2022 endogenous Cushing syndrome Cortendo AB Completed No outcome recorded
Phase 3 NCT03277690 Sep 2017 → Jun 2020 endogenous Cushing syndrome Cortendo AB Completed No outcome recorded
Phase 3 NCT01838551 Aug 2014 → Apr 2018 endogenous Cushing syndrome Cortendo AB Completed No outcome recorded

Evidence & citations 4 cited values

Every value below carries the sentence it was read from. 8 sources stand behind the page.

FieldValueCited text
Known as Levoketoconazole ClinicalTrials.gov intervention name — accepted as the source's own label NCT03880825
5

NCT04212000

NCT03768388

NCT03621280

NCT01838551

NCT03277690

Known as 2S,4R-ketoconazole “An Open-label Extension Study of Levoketoconazole (2S,4R-ketoconazole) in the Treatment of Endogenous Cushing's Syndrome” NCT03621280
Known as DIO-902 ClinicalTrials.gov intervention name — accepted as the source's own label NCT00494663
1

NCT00622089

Route Oral “The study drug is a tablet and will be taken by mouth with water.” NCT00494663