Drugs / Estazolam
last change Mar 2026 re-read 2 minutes ago

Estazolam

also known as ABBOTT-47631 · Estazolam civ · Eurodin · NSC-290818 · Prosom

Small molecule

Developed for
insomnia · cancer · sleep disorder, initiating and maintaining sleep
Investigated by
Boehringer Ingelheim · Hui Zhu · Minamihanno Hospital · Qinghai Red Cross Hospital

Regulatory milestones approvals, filings & regulatory actions · 1 recorded

MilestoneJurisdictionBrandIndicationDateSentence it was read from
Approved US (FDA) PROSOM 1990-12-26 fda.gov

Trials 4 · a red edge is where a trial was stopped

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PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 32 trials
Phase 3 NCT06859190 Mar 2025 → Mar 2026 overdue cancer, insomnia Qinghai Red Cross Hospital Recruiting No outcome recorded
Phase 3 NCT00347295 Jun 2006 → Jan 2007 sleep disorder, initiating and maintaining sleep Boehringer Ingelheim Completed No outcome recorded
Phase 42 trials
Phase 4 NCT07306494 Jan 2026 → Apr 2028 expected insomnia Hui Zhu Not yet recruiting No outcome recorded
Phase 4 NCT00707915 Jan 2008 → Jul 2010 Minamihanno Hospital Completed No outcome recorded
Also used as a comparator or background therapy in 5 trials
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 42 trials
Phase 4 NCT03997058 Comparator Mar 2019 → Jun 2020 sleep disorder, initiating and maintaining sleep The First Affiliated Hospital, Guangzhou University of Traditional Chinese Medicine Unknown No outcome recorded
Phase 4 NCT00956319 Comparator May 2009 → Nov 2010 insomnia, sleep disorder, initiating and maintaining sleep Astellas Pharma Inc Completed No outcome recorded
Phase not applicable3 trials
NCT06258226 Comparator Jul 2024 → Jun 2025 Wenzhou Central Hospital Unknown No outcome recorded
NCT06212934 Comparator Mar 2024 → Mar 2025 insomnia Beijing Hospital of Traditional Chinese Medicine Unknown No outcome recorded
NCT05452577 Comparator Jan 2021 → May 2023 circadian rhythm sleep disorder, insomnia The First Affiliated Hospital with Nanjing Medical University Completed No outcome recorded

Evidence & citations 8 cited values

Every value below carries the sentence it was read from. 10 sources stand behind the page.

FieldValueCited text
Known as Estazolam “BZD-derivative hypnotics will include brotizolam, flunitrazepam, etizolam, quazepam, estazolam, nitrazepam, flurazepam, and diazepam.” NCT00707915
8

“A Randomized Controlled Trial of Auricular Acupressure in Treating Estazolam-dependent Insomnia” NCT06258226

NCT05452577

NCT06859190

NCT00347295

NCT00956319

NCT03997058

NCT07306494

NCT06212934

Known as ABBOTT-47631 ChEMBL registry synonym — accepted as the source's own label CHEMBL285674
Known as Estazolam civ ChEMBL registry synonym — accepted as the source's own label CHEMBL285674
Known as Eurodin ChEMBL registry synonym — accepted as the source's own label CHEMBL285674
Known as NSC-290818 ChEMBL registry synonym — accepted as the source's own label CHEMBL285674
Known as Prosom ChEMBL registry synonym — accepted as the source's own label CHEMBL285674
Modality Small molecule CHEMBL285674
Route Oral “Participants will take estazolam 1mg 30min prior to bedtime everyday.” NCT06212934