Drugs / Chlorotoxin-CD28-CD3z-CD19t-expressing CAR T-cells
last change Feb 2020 re-read 3 minutes ago

Chlorotoxin-CD28-CD3z-CD19t-expressing CAR T-cells

Cell therapy

Developed for
glioblastoma · grade II glioma · grade III glioma
Investigated by
City of Hope Medical Center · National Cancer Institute (NCI)

Trials 1

20202021202220232024202520262027
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 1 NCT04214392 Feb 2020 → May 2027 expected glioblastoma, grade II glioma, grade III glioma City of Hope Medical Center Active not recruiting No outcome recorded

Evidence & citations 4 cited values

Every value below carries the sentence it was read from. 1 source stands behind the page.

FieldValueCited text
Known as Chlorotoxin-CD28-CD3z-CD19t-expressing CAR T-cells “Chlorotoxin-CD28-CD3z-CD19t-expressing CAR T-cells” NCT04214392 ↗
Action Deplete “kill tumor cells” NCT04214392 ↗
Modality Cell therapy “chimeric antigen receptor (CAR) T cells with a chlorotoxin tumor-targeting domain” NCT04214392 ↗
Route Other “Given via ICT delivery” NCT04214392 ↗