Drugs / prinomastat
last change Jan 2002 re-read 2 minutes ago

prinomastat

also known as AG3340 · KB-R-9896

Small molecule

Developed for
central nervous system neoplasm · lung cancer · prostate cancer
Investigated by
Pfizer

Trials 3 · a red edge is where a trial was stopped

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PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 21 trial
Phase 2 NCT00004200 Oct 1999 → Jan 2002 central nervous system neoplasm Pfizer Completed No outcome recorded
Phase 32 trials
Phase 3 NCT00004199 Mar 1999 → Jul 2001 lung cancer Pfizer Completed No outcome recorded
Phase 3 NCT00003343 Mar 1998 → Jan 2001 prostate cancer Pfizer Completed No outcome recorded

Evidence & citations 6 cited values

Every value below carries the sentence it was read from. 4 sources stand behind the page.

FieldValueCited text
Known as prinomastat ClinicalTrials.gov intervention name — accepted as the source's own label NCT00004200
2

NCT00004199

NCT00003343

Known as AG3340 “A Randomized, Double-Blind, Placebo-Controlled, Phase III Study of the Matrix Metalloprotease Inhibitor Prinomastat (AG3340) in Combination With Gemcitabine and Cisplatin in...” NCT00004199
1

“treated with prinomastat (AG3340) or placebo and temozolomide following radiotherapy.” NCT00004200

Known as KB-R-9896 ChEMBL registry synonym — accepted as the source's own label CHEMBL75094
Action Inhibit “Matrix Metalloprotease Inhibitor Prinomastat” NCT00004199
Modality Small molecule CHEMBL75094
Route Oral “Patients receive oral prinomastat or placebo twice daily” NCT00004199