Drugs / ASLAN003
last change Oct 2024 re-read 3 minutes ago

ASLAN003

also known as Farudodstat

Small molecule targets DHODH via inhibition

Developed for
acute myeloid leukemia · alopecia areata
Investigated by
ASLAN Pharmaceuticals

Trials 4

20142015201620172018201920202021202220232024202520262027
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 12 trials
Phase 1 NCT02342652 Oct 2014 → Mar 2015 — ASLAN Pharmaceuticals Completed No outcome recorded
Phase 1 NCT01992367 Aug 2013 → May 2014 — ASLAN Pharmaceuticals Completed No outcome recorded
Phase 22 trials
Phase 2 NCT05865041 Apr 2023 → Sep 2024 alopecia areata ASLAN Pharmaceuticals Unknown No outcome recorded
Phase 2 NCT03451084 Jan 2018 → Sep 2019 acute myeloid leukemia ASLAN Pharmaceuticals Completed No outcome recorded

Evidence & citations 6 cited values

Every value below carries the sentence it was read from. 5 sources stand behind the page.

FieldValueCited text
Known as ASLAN003 ClinicalTrials.gov intervention name — accepted as the source's own label NCT01992367 ↗
2

NCT03451084 ↗

NCT02342652 ↗

Known as Farudodstat ClinicalTrials.gov intervention name — accepted as the source's own label NCT05865041 ↗
Action Inhibit “ASLAN003 (N-aryl substituted aminoaryloic acid derivative), which is a DHODH inhibitor” NCT02342652 ↗
1

“Dihydroorotate dehydrogenase inhibitor” CHEMBL2263632 ↗

Modality Small molecule — CHEMBL2263632 ↗
Route Oral “Administration route: Oral” NCT02342652 ↗
Target DHODH “Dihydroorotate dehydrogenase inhibitor” CHEMBL2263632 ↗