Drugs / BAFISONTAMAB
last change Jul 2026 re-read 2 minutes ago

BAFISONTAMAB

also known as EMB-01 · FIT-013a

Monoclonal antibody targets EGFR, MET via inhibition

Developed for
colorectal cancer · metastatic neoplasm · non-small cell lung carcinoma · carcinoid tumor
Investigated by
Shanghai EpimAb Biotherapeutics Co., Ltd. · Labcorp Corporation of America Holdings, Inc · Covance

Trials 5 · a red edge is where a trial was stopped

PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 11 trial
Phase 1 NCT07649655 Jul 2026 → Mar 2028 expected colorectal cancer Shanghai EpimAb Biotherapeutics Co., Ltd. Not yet recruiting No outcome recorded
Phase 1/23 trials
Phase 1/2 NCT05498389 Jun 2023 → Jul 2024 non-small cell lung carcinoma Shanghai EpimAb Biotherapeutics Co., Ltd. Unknown No outcome recorded
Phase 1/2 NCT05176665 Oct 2021 → Dec 2025 overdue carcinoid tumor, metastatic neoplasm Shanghai EpimAb Biotherapeutics Co., Ltd. Recruiting No outcome recorded
Phase 1/2 NCT03797391 Dec 2018 → Mar 2025 metastatic neoplasm, non-small cell lung carcinoma Shanghai EpimAb Biotherapeutics Co., Ltd. Unknown No outcome recorded
Phase 21 trial
Phase 2 NCT07314294 Dec 2025 → Dec 2027 expected colorectal cancer Shanghai EpimAb Biotherapeutics Co., Ltd. Recruiting No outcome recorded

Evidence & citations 8 cited values

Every value below carries the sentence it was read from. 6 sources stand behind the page.

FieldValueCited text
Known as BAFISONTAMAB ChEMBL registry synonym — accepted as the source's own label CHEMBL4594472
Known as EMB-01 ClinicalTrials.gov intervention name — accepted as the source's own label NCT07649655
4

NCT05176665

NCT03797391

NCT07314294

NCT05498389

Known as FIT-013a ChEMBL registry synonym — accepted as the source's own label CHEMBL4594472
Action Inhibit “EMB-01 and osimertinib may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth in this type of cancer.” NCT05498389
Modality Monoclonal antibody CHEMBL4594472
Route Intravenous “receive intravenous infusions of EMB01” NCT03797391
Target EGFR “Epidermal growth factor receptor (EGFR)” NCT03797391
Target MET “c-Mesenchymal-Epithelial Transition (cMet)” NCT03797391