Drugs / MP0317
last change May 2026 re-read 2 minutes ago

MP0317

Protein / enzyme biologic targets CD40, FAP via activation

Developed for
biliary tract cancer · cancer
Investigated by
Molecular Partners AG · Centre Hospitalier Universitaire de Besancon

Trials 2 · a red edge is where a trial was stopped

20222023202420252026202720282029
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 11 trial
Phase 1 NCT05098405 Oct 2021 → Jan 2024 cancer Molecular Partners AG Terminated No outcome recorded
Phase 21 trial
Phase 2 NCT07036380 Dec 2025 → Nov 2028 expected biliary tract cancer Centre Hospitalier Universitaire de Besancon Recruiting No outcome recorded

Evidence & citations 6 cited values

Every value below carries the sentence it was read from. 4 sources stand behind the page.

FieldValueCited text
Known as MP0317 ClinicalTrials.gov intervention name — accepted as the source's own label NCT07036380
1

NCT05098405

Action Activate “α-FAPxCD40 activation of CD40 depends on binding to fibroblast activation protein (FAP)” PMID 35319751 May 2022
Modality Protein / enzyme biologic “MP0317 (FAP x CD40 DARPin)” PMID 42067655 May 2026
Route Intravenous “Study treatment will be administered as an intravenous (IV) infusion” NCT05098405
Target CD40 “a DARPin® drug candidate targeting fibroblast activation protein (FAP) and CD40.” NCT05098405
Target FAP “a DARPin® drug candidate targeting fibroblast activation protein (FAP) and CD40.” NCT05098405