Drugs / thiethylperazine
thiethylperazine
also known as
GS-95 · NSC-130044 · Thiethylperazine dimalate · Thiethylperazine dimaleate · THIETHYLPERAZINE MALATE · THIETHYLPERAZINE MALEATE · Thietylperazine maleate · Tietilperazina · +1 more
Small molecule targets DRD2 via inhibition
Regulatory milestones approvals, filings & regulatory actions · 1 recorded
| Milestone | Jurisdiction | Brand | Indication | Date | Sentence it was read from |
|---|---|---|---|---|---|
| Approved | US (FDA) | TORECAN | — | 1961-07-18 | fda.gov ↗ |
Trials 0
| Phase | Registry id | Dates | Indication | Sponsor | Status | Outcome |
|---|---|---|---|---|---|---|
| Comparator or background therapy3 trials | ||||||
| — | NCT07084753 Comparator | Jul → Sep 2025 overdue | obesity disorder | IVO JURISIC | Not yet recruiting | No outcome recorded |
| — | NCT03956446 Background | Sep 2014 → Dec 2027 expected | tick-borne encephalitis | University Medical Centre Ljubljana | Recruiting | No outcome recorded |
| — | NCT02463942 Background | Sep 2014 → Sep 2020 | tick-borne encephalitis | University Medical Centre Ljubljana | Unknown | No outcome recorded |
Evidence & citations 14 cited values
Every value below carries the sentence it was read from. 4 sources stand behind the page.
| Field | Value | Cited text |
|---|---|---|
| Known as | Thiethylperazine | “Patients will receive symptomatic therapy with antipyretics, analgetics, antiemetics, and parenteral hydration: metamizole, Analgin®, paracetamol, Lekadol®, thiethylperazine,...” NCT02463942 ↗2“Patients will receive symptomatic therapy with antipyretics, analgetics, antiemetics, and parenteral hydration: metamizole, Analgin®, paracetamol, Lekadol®, thiethylperazine,...” NCT03956446 ↗ |
| Known as | GS-95 | ChEMBL registry synonym — accepted as the source's own label CHEMBL1378 ↗ |
| Known as | NSC-130044 | ChEMBL registry synonym — accepted as the source's own label CHEMBL1378 ↗ |
| Known as | Thiethylperazine dimalate | ChEMBL registry synonym — accepted as the source's own label CHEMBL1378 ↗ |
| Known as | Thiethylperazine dimaleate | ChEMBL registry synonym — accepted as the source's own label CHEMBL1378 ↗ |
| Known as | THIETHYLPERAZINE MALATE | ChEMBL registry synonym — accepted as the source's own label CHEMBL1378 ↗ |
| Known as | THIETHYLPERAZINE MALEATE | ChEMBL registry synonym — accepted as the source's own label CHEMBL1378 ↗ |
| Known as | Thietylperazine maleate | ChEMBL registry synonym — accepted as the source's own label CHEMBL1378 ↗ |
| Known as | Tietilperazina | ChEMBL registry synonym — accepted as the source's own label CHEMBL1378 ↗ |
| Known as | Torecan | ChEMBL registry synonym — accepted as the source's own label CHEMBL1378 ↗ |
| Action | Inhibit | “Dopamine D2 receptor antagonist” CHEMBL1378 ↗ |
| Modality | Small molecule | — CHEMBL1378 ↗ |
| Route | Intravenous | “patients receive dexamethasone (8 mg) and thiethylperazine (6.5 mg) intravenously” NCT07084753 ↗ |
| Target | DRD2 | “Dopamine D2 receptor antagonist” CHEMBL1378 ↗ |