Triferic
Regulatory milestones approvals, filings & regulatory actions · 1 recorded
| Milestone | Jurisdiction | Brand | Indication | Date | Sentence it was read from |
|---|---|---|---|---|---|
| Approved | US (FDA) | TRIFERIC | — | 2015-01-23 | fda.gov ↗ |
Trials 19 · a red edge is where a trial was stopped
Also used as a comparator or background therapy in 4 trials
| Phase | Registry id | Dates | Indication | Sponsor | Status | Outcome |
|---|---|---|---|---|---|---|
| Phase 11 trial | ||||||
| Phase 1 | NCT00867867 Comparator | Oct 2003 → Jun 2008 | Helicobacter pylori infectious disease | International Centre for Diarrhoeal Disease Research, Bangladesh | Completed | No outcome recorded |
| Phase 21 trial | ||||||
| Phase 2 | NCT01286012 Comparator | Jan 2011 → Jan 2013 | end stage renal failure | Rockwell Medical Technologies, Inc. | Completed | No outcome recorded |
| Phase 32 trials | ||||||
| Phase 3 | NCT01322347 Comparator | Apr 2011 → Jan 2014 | end stage renal failure | Rockwell Medical Technologies, Inc. | Completed | No outcome recorded |
| Phase 3 | NCT01320202 Comparator | Mar 2011 → May 2013 | chronic renal failure syndrome | Rockwell Medical Technologies, Inc. | Completed | No outcome recorded |
Evidence & citations 15 cited values
Every value below carries the sentence it was read from. 25 sources stand behind the page.
| Field | Value | Cited text |
|---|---|---|
| Known as | Triferic | “Ferric pyrophosphate citrate (Triferic™) administration via the dialysate” PMID 26175145 ↗ Jul 2015 |
| Known as | Actiferol | “Ferric pyrophosphate (powder preparation in sachets: Actiferol, SunActive Fe, Sequoia, Poland) in a single daily dose.” NCT02242188 ↗ |
| Known as | FePP | “a complementary food (CF) fortified with sodium iron EDTA (NaFeEDTA) plus either ferrous fumarate (FeFum) or ferric pyrophosphate (FePP)” PMID 28708072 ↗ Jul 2017 |
| Known as | Ferric pyrophosphate | “Sucrosomial iron (Sideral® Forte) is a preparation of ferric pyrophosphate conveyed within a phospholipid membrane associated with ascorbic acid, is a new-generation oral iron...” NCT02916654 ↗3“The current premix contains 3.8 mg in the form of ferric pyrophosphate, which is less bioavailable than the 3.8 mg ferrous fumarate in the optimized formula.” NCT01634945 ↗ “Ferric pyrophosphate (powder preparation in sachets: Actiferol, SunActive Fe, Sequoia, Poland) in a single daily dose.” NCT02242188 ↗ |
| Known as | ferric pyrophosphate citrate | “Triferic (ferric pyrophosphate citrate, FPC), an iron-replacement product, is an iron complex in which iron(III) is bound to pyrophosphate and citrate.” NCT04042324 ↗3“Ferric pyrophosphate citrate (FPC) is a water-soluble iron salt administered via dialysate to supply iron directly to transferrin.” PMID 26154926 ↗ Jul 2015 “Ferric pyrophosphate citrate (Triferic™) administration via the dialysate” PMID 26175145 ↗ Jul 2015 “Ferric Pyrophosphate Citrate” NCT04239391 ↗ |
| Known as | FPC | “Administration of ferric pyrophosphate citrate (FPC, Triferic™) via
hemodialysate may allow replacement of ongoing uremic and hemodialysis-related
iron losses.” PMID 26175145 ↗ Jul 20152“Triferic (ferric pyrophosphate citrate, FPC), an iron-replacement product, is an iron complex in which iron(III) is bound to pyrophosphate and citrate.” NCT04042324 ↗ “Ferric pyrophosphate citrate (FPC) is a water-soluble iron salt administered via dialysate to supply iron directly to transferrin.” PMID 26154926 ↗ Jul 2015 |
| Known as | Iron | “Iron (micronized microencapsulated ferric pyrophosphate), 1 mg/kg, or placebo (maltodextrin) once daily from age 4 to 9 months.” PMID 38739382 ↗ Jul 2024 |
| Known as | oral liposomal iron | ClinicalTrials.gov intervention name — accepted as the source's own label NCT02760940 ↗ |
| Known as | Sequoia | “Ferric pyrophosphate (powder preparation in sachets: Actiferol, SunActive Fe, Sequoia, Poland) in a single daily dose.” NCT02242188 ↗ |
| Known as | SFP | “Soluble Ferric Pyrophosphate (SFP)” NCT01320202 ↗1“soluble ferric pyrophosphate (SFP)” NCT00604565 ↗ |
| Known as | Soluble Ferric Pyrophosphate | ClinicalTrials.gov intervention name — accepted as the source's own label NCT01320202 ↗ |
| Known as | SunActive Fe | “Ferric pyrophosphate (powder preparation in sachets: Actiferol, SunActive Fe, Sequoia, Poland) in a single daily dose.” NCT02242188 ↗ |
| Known as | Triferic AVNU | ClinicalTrials.gov intervention name — accepted as the source's own label NCT05110768 ↗ |
| Modality | Other / unclassified | “Triferic is an iron salt” NCT02909153 ↗ |
| Route | Other | “administered via dialysate” PMID 26154926 ↗ Jul 2015 |