Drugs / Flotetuzumab

Trials 8 · a red edge is where a trial was stopped

PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 13 trials
Phase 1 NCT05506956 Oct 2022 → Jun 2024 acute myeloid leukemia Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins Completed No outcome recorded
Phase 1 NCT04681105 Nov 2020 → Aug 2025 B-cell acute lymphoblastic leukemia, CD4+/CD56+ hematodermic neoplasm, Hodgkins lymphoma, T-cell acute lymphoblastic leukemia +4 City of Hope Medical Center Completed No outcome recorded
Phase 1 NCT04158739 Jan 2020 → Sep 2022 overdue acute myeloid leukemia Children's Oncology Group Active not recruiting No outcome recorded
Phase 1/21 trial
Phase 1/2 NCT02152956 Jun 2014 → Jul 2022 acute myeloid leukemia MacroGenics Terminated No outcome recorded
Phase 23 trials
Phase 2 NCT05063123 Jan 2022 → Aug 2024 acute myeloid leukemia HOVON Foundation Withdrawn No outcome recorded
Phase 2 NCT04582864 May 2021 → Mar 2024 acute myeloid leukemia Washington University School of Medicine Terminated No outcome recorded
Phase 2 NCT03739606 Oct 2020 CD4+/CD56+ hematodermic neoplasm, Hodgkins lymphoma, Philadelphia-positive myelogenous leukemia, acute biphenotypic leukemia +3 City of Hope Medical Center Withdrawn No outcome recorded
Phase not stated1 trial
NCT04678466 acute myeloid leukemia MacroGenics No longer available No outcome recorded

Evidence & citations 8 cited values

Every value below carries the sentence it was read from. 9 sources stand behind the page.

FieldValueCited text
Known as Flotetuzumab “This phase II trial studies how well flotetuzumab works in treating patients with CD123 positive blood cancer that has come back or does not respond to treatment.” NCT03739606
7

NCT05063123

NCT02152956

NCT05506956

NCT04678466

NCT04582864

NCT04158739

NCT04681105

Known as MGD-006 ChEMBL registry synonym — accepted as the source's own label CHEMBL3990038
Known as NSC#808294 “A Phase 1 Trial of the CD123 X CD3 DART Molecule Flotetuzumab (NSC#808294) in Children, Adolescents, and Young Adults With Relapsed or Refractory Acute Myeloid Leukemia” NCT04158739
Known as RES-234 ChEMBL registry synonym — accepted as the source's own label CHEMBL3990038
Known as S-80880 ChEMBL registry synonym — accepted as the source's own label CHEMBL3990038
Modality Monoclonal antibody “Immunotherapy with monoclonal antibodies, such as flotetuzumab, may help the body's immune system attack the cancer” NCT03739606
Route Intravenous “Given IV” NCT03739606
Target IL3RA “Interleukin-3 receptor subunit alpha binding agent” CHEMBL3990038