Drugs / TEZ/IVA
last change Oct 2018 re-read 2 minutes ago

TEZ/IVA

targets CFTR via restoration

Developed for
cystic fibrosis
Investigated by
Vertex Pharmaceuticals Incorporated

Trials 1 · a red edge is where a trial was stopped

201820192020202120222023202420252026
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 2 NCT03224351 Aug 2017 → Feb 2018 cystic fibrosis Vertex Pharmaceuticals Incorporated Completed No outcome recorded

Evidence & citations 4 cited values

Every value below carries the sentence it was read from. 2 sources stand behind the page.

FieldValueCited text
Known as TEZ/IVA ClinicalTrials.gov intervention name — accepted as the source's own label NCT03224351
Action Restore “developed to restore the function of Phe508del CFTR protein” PMID 30334693 Oct 2018
Route Oral “TEZ/IVA fixed-dose combination tablet for oral administration.” NCT03224351
Target CFTR “restore the function of Phe508del CFTR protein” PMID 30334693 Oct 2018