Drugs / DTRMWXHS-12
last change Dec 2024 re-read 2 minutes ago

DTRMWXHS-12

targets BTK via inhibition

Developed for
B-cell chronic lymphocytic leukemia · diffuse large B-cell lymphoma · follicular lymphoma · mantle cell lymphoma · Richter transformation
Investigated by
Zhejiang DTRM Biopharma

Trials 4 · a red edge is where a trial was stopped

PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 13 trials
Phase 1 NCT03836768 Jan 2019 → Nov 2021 mantle cell lymphoma Zhejiang DTRM Biopharma Completed No outcome recorded
Phase 1 NCT02900716 Sep 2016 → Nov 2020 B-cell chronic lymphocytic leukemia Zhejiang DTRM Biopharma Completed No outcome recorded
Phase 1 NCT02891590 Sep 2016 → Feb 2019 B-cell chronic lymphocytic leukemia Zhejiang DTRM Biopharma Completed No outcome recorded
Phase 21 trial
Phase 2 NCT04305444 Apr 2020 → Dec 2024 B-cell chronic lymphocytic leukemia, Richter transformation, diffuse large B-cell lymphoma, follicular lymphoma Zhejiang DTRM Biopharma Terminated No outcome recorded

Evidence & citations 4 cited values

Every value below carries the sentence it was read from. 4 sources stand behind the page.

FieldValueCited text
Known as DTRMWXHS-12 “Phase Ia explored escalating doses of a monotherapy of a novel Bruton's Tyrosine Kinase (BTK) inhibitor, DTRMWXHS-12.” NCT04305444
3

NCT02891590

NCT02900716

NCT03836768

Action Inhibit “BTK Inhibitor DTRMWXHS-12” NCT02891590
Route Oral “multiple dose oral administration of DTRMWXHS-12 capsule” NCT02891590
Target BTK BTK Inhibitor DTRMWXHS-12” NCT02891590