Drugs / tissue-type plasminogen activator
last change Dec 2020 re-read 2 minutes ago

tissue-type plasminogen activator

also known as rt-PA · t-PA

Protein / enzyme biologic

Developed for
myocardial infarction
Investigated by
National Heart, Lung, and Blood Institute (NHLBI)

Trials 1 · a red edge is where a trial was stopped

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PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 3 NCT00000472 Apr 1989 → Jun 1995 coronary artery disorder, myocardial infarction, myocardial ischemia National Heart, Lung, and Blood Institute (NHLBI) Completed No outcome recorded

Evidence & citations 4 cited values

Every value below carries the sentence it was read from. 2 sources stand behind the page.

FieldValueCited text
Known as tissue-type plasminogen activator “The Thrombolysis in Myocardial Ischemia (TIMI) 3B trial compared recombinant tissue-type plasminogen activator (rt-PA) (35-80 mg) with placebo and early catheterisation with...” PMID 33262195 Dec 2020
Known as rt-PA “The Thrombolysis in Myocardial Ischemia (TIMI) 3B trial compared recombinant tissue-type plasminogen activator (rt-PA) (35-80 mg) with placebo and early catheterisation with...” PMID 33262195 Dec 2020
Known as t-PA “The Thrombolysis in Myocardial Ischemia Trial (TIMI III) focused on unstable angina and non-Q-wave myocardial infarction. The trial was designed to determine by coronary...” NCT00000472
Modality Protein / enzyme biologic “The Thrombolysis in Myocardial Ischemia (TIMI) 3B trial compared recombinant tissue-type plasminogen activator (rt-PA) (35-80 mg) with placebo and early catheterisation with...” PMID 33262195 Dec 2020