Drugs / HPB-092
last change Dec 2025 re-read 3 minutes ago

HPB-092

Small molecule targets FLT3, IRAK4 via inhibition

Developed for
acute myeloid leukemia
Investigated by
Hangzhou Polymed Biopharmaceuticals, Inc.

Trials 1

20262027
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 1 NCT07137637 Dec 2025 → Sep 2027 expected acute myeloid leukemia Hangzhou Polymed Biopharmaceuticals, Inc. Not yet recruiting No outcome recorded

Evidence & citations 6 cited values

Every value below carries the sentence it was read from. 1 source stands behind the page.

FieldValueCited text
Known as HPB-092 ClinicalTrials.gov intervention name — accepted as the source's own label NCT07137637 ↗
Action Inhibit “This novel small molecule selectively inhibits both FLT3 and interleukin-1 receptor-associated kinase 4 (IRAK4).” NCT07137637 ↗
Modality Small molecule “This novel small molecule selectively inhibits both FLT3 and interleukin-1 receptor-associated kinase 4 (IRAK4).” NCT07137637 ↗
Route Oral “HPB-092 is formulated as a tablet for oral administration, taken twice daily (BID) over consecutive 28-day cycles.” NCT07137637 ↗
Target FLT3 “This novel small molecule selectively inhibits both FLT3 and interleukin-1 receptor-associated kinase 4 (IRAK4).” NCT07137637 ↗
Target IRAK4 “This novel small molecule selectively inhibits both FLT3 and interleukin-1 receptor-associated kinase 4 (IRAK4).” NCT07137637 ↗