Drugs / ABI-6250
last change May 2026 re-read 3 minutes ago

ABI-6250

Investigated by
Assembly Biosciences

Trials 1

PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 1 NCT06740474 Jan → Jul 2025 hepatitis D virus infection Assembly Biosciences Completed No outcome recorded

News releases announcing trial results or a regulatory action · 3

DateIssuerRelease
2025-08-06 Assembly Biosciences Results Assembly Biosciences Reports Interim Phase 1a Data from Clinical Study of Oral Entry Inhibitor Candidate ABI-6250 for Hepatitis Delta Virus assemblybio.com ↗
2025-05-07 Assembly Biosciences Results New Preclinical Data for Assembly Biosciences’ Oral Hepatitis D Virus Entry Inhibitor ABI-6250 and Next-Generation Hepatitis B Virus Capsid Assembly Modulator ABI-4334 Presented at the EASL Congress 2025 assemblybio.com ↗
Our late-breaker poster highlights ABI-6250’s preclinical profile and potential as a once-daily oral therapy for chronic HDV infection, a severe form of viral hepatitis with limited treatment options available.
2024-06-05 Assembly Biosciences Results Assembly Biosciences Presents New Data Highlighting Hepatitis D Virus Entry Inhibitor ABI-6250 at the EASL Congress™ 2024 assemblybio.com ↗
Results from preclinical evaluation included in this presentation demonstrate that ABI-6250 can effectively inhibit, at low nanomolar levels, HDV infection of the most prevalent genotypes (HDV-1,-2 and-3) in HepG2-NTCP cells.

Evidence & citations 1 cited value

Every value below carries the sentence it was read from. 1 source stands behind the page.

FieldValueCited text
Known as ABI-6250 ClinicalTrials.gov intervention name — accepted as the source's own label NCT06740474 ↗